Impairment of bone mass development in children with chronic cholestatic liver disease.

Objective: To analyse aspects of mineral metabolism, bone mineral density (BMD), bone remodelling activity and serum IGF-1 levels in children with chronic cholestatic disease (CCLD).

Patients And Measurements: A total of 13 children with chronic cholestatic liver disease (CCLD; mean age 7.2 +/- 4.