Publications by authors named "Adriana Roussos"
Article Synopsis
- Obesity is a complex disorder influenced by a mix of genetics and environmental factors, with several gene variants linked to food intake and leptin's effects in the brain.
- Advances in next-generation sequencing have revealed a higher incidence of genetic factors associated with obesity than previously thought.
- Early diagnosis of both syndromic and non-syndromic monogenic obesity is crucial to prevent the use of ineffective treatments like surgery or non-specific medications.
This document updates the "Clinical practice guidelines for the prevention, diagnosis and treatment of obesity" issued by the Nutrition Committee of the Argentine Pediatric Society, published in Archivos Argentinos de Pediatría in 2011. Obesity has a multifactorial etiology. It is recommended to diagnose it taking into account anthropometry, personal and family history, and clinical data that indicate complications (sleep apnea, elevated alanine transaminase and/or glycemia, and other components of the metabolic syndrome).
View Article and Find Full Text PDFObesity and hypertension are increasing medical problems in adolescents. Serotonin transporter (5-HTT) is involved in mood and eating disturbances. Encoded by the gene SLC6A4, the promoter shows functional insertion/deletion alleles: long (L) and short (S).
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