Publications by authors named "Adriana Porta Miche Hirschfeld"
Life-threatening variceal bleeding after liver transplantation and extensive portal vein thrombosis: Desperate times call for desperate measures.
AndréMoreira de Assis José Andrade de Carvalho Melo Willian Yoshinori Kawakami Airton Mota Moreira Francisco Cesar Carnevale Adriana Porta Miche Hirschfeld
Pediatr Transplant
December 2023
Background: The management of complex, intra- and extrahepatic portal vein thrombosis (PVT) after liver transplantation (LT) is challenging. Although most of the patients remain asymptomatic or oligosymptomatic in the chronic setting, some of them may develop severe portal hypertension and related complications, notably gastrointestinal (GI) bleeding. In the emergency scenario, clinical and endoscopic treatments as well as intensive support constitute the bases of conservative management, while more definitive treatment options such as surgical shunting and retransplantation are related to high morbidity rates.
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- The study investigates outcomes of liver transplantation (LT) in patients with cirrhosis and hypoxia, focusing on those with different levels of arterial oxygen pressure (PaO).
- Patients were split into two groups based on their PaO levels, with significant differences noted in their need for supplemental oxygen, mechanical ventilation (MV) duration, and hospital stays.
- Despite differences in recovery needs, survival rates at 90 months were comparable between the groups, indicating that severe hypoxia does not drastically impact long-term survival post-transplant.