Publications by authors named "Adriana M Maia"
HPLC stability-indicating method was validated for Vitamin C (ascorbic acid) in semisolid pharmaceutical/cosmetic formulations containing glutathione and sodium metabisulfite, as antioxidants. The described procedure included a reliable, precise, accurate and specific method determination employing a 250mm x 4.6mm C(18) column, 0.
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- Vitamin C plays a crucial role in skin health through collagen synthesis, depigmentation, and antioxidant effects, but it is highly unstable in various conditions, necessitating effective antioxidant systems for stability in cosmetic products.
- The research aimed to develop O/W emulsions and aqueous gels containing vitamin C, testing the effects of antioxidants sodium metabisulfite (SMB) and glutathione (GLT) on its stability.
- Stability tests showed that formulations with SMB or GLT maintained over 90% of vitamin C content under controlled conditions, confirming that these antioxidants are essential for preserving vitamin C in cosmetics.