Publications by authors named "Adriana Guimaraes Sa"
Predictors of Hepatic Fibrosis in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
Biomedicines
November 2024
Background/objectives: Approximately 25% of the world's population and more than 60% of patients with type 2 diabetes (T2D) have metabolic-dysfunction-associated steatotic liver disease (MASLD). The association between these pathologies is an important cause of morbidity and mortality in Brazil and worldwide due to the high frequency of advanced fibrosis and cirrhosis. The objective of this study was to determine the epidemiologic and clinical-laboratory profile of patients with T2D and MASLD treated at an endocrinology reference service in a state in northeastern Brazil, and to investigate the association of liver fibrosis with anthropometric and laboratory measurements.
View Article and Find Full Text PDFRelationship Between C-Peptide Levels, Clinical Features, and Serum Data in a Brazilian Type 1 Diabetes Population with Large Variations in Genomic Ancestry.
Int J Mol Sci
October 2024
Article Synopsis
- - Type 1 diabetes (T1D) is a chronic condition where the immune system attacks beta cells in the pancreas that produce insulin; C-peptide, released alongside insulin, is a helpful marker for evaluating pancreatic function due to its longer lifespan in the body.
- - A study involving 95 T1D patients focused on the levels of C-peptide and its relationship with factors like age, revealing that nearly 30% had some remaining insulin secretion, primarily linked to their age at diagnosis.
- - No significant differences were found in metabolic control or microvascular complications based on C-peptide levels, and it was noted that ancestry did not affect residual C-peptide function; future research should explore additional factors like HLA and pancreatic auto
Healthy lifestyle and genomic ancestry related to good glycemic control in type 1 diabetes patients from Northeastern Brazil: a hierarchical analysis.
Front Endocrinol (Lausanne)
October 2023
Introduction: This study aimed to investigate the sociodemographic factors, dietary adherence, regular physical activity, and genomic ancestry percentage associated with good glycemic control in Brazilian patients with type 1 diabetes (T1D) using a hierarchical approach.
Methods: A cross-sectional study was conducted in 152 T1D patients. Glycated hemoglobin (HbA1C) levels were measured to evaluate the glycemic control status (good, moderate, or poor).
We aimed to evaluate the Health-related quality of life (HRQoL) of Type 1 diabetes mellitus (T1D) patients in an admixed Brazilian population. This is a cross-sectional study with 152 T1D patients. HRQoL information was obtained from two self-completed questionnaires: Short Form-6 dimensions and EuroQol-5 dimensions with visual analog scale.
View Article and Find Full Text PDFHigher Income and Integration into the Workforce Are the Main Factors Associated with Quality of Life in Acromegalic Patients in Northeastern Brazil.
Int J Endocrinol
February 2018
Objective: To identify the factors associated with quality of life in patients with acromegaly with follow-up at the referral service in neuroendocrinology of the state of Maranhão, northeast Brazil.
Methods: The Acromegaly Quality of Life Questionnaire (Acro-QoL) was used. Factors independently associated with quality of life were identified using multivariate linear regression, with values < 0.