Publications by authors named "Adriana Esteban"
is the etiological agent of zoonotic visceral leishmaniasis (ZVL). The disease is endemic in Central and South America, Central and South East Asia, and the Mediterranean basin. Dogs are the main reservoir, with an estimated prevalence of approximately 2.
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- Leishmania infantum causes zoonotic visceral leishmaniasis (ZVL), a public health issue in the Mediterranean and South America, particularly affecting HIV patients and dogs, which are the main reservoirs.
- Researchers developed a DNA vaccine using a new plasmid vector (pPAL) that enhances safety, protecting Beagle dogs through a novel prime-boost vaccination method.
- The study also explores the combination of the LACK gene with IL12 to potentially improve treatment outcomes in dogs that do not respond to conventional therapies, highlighting the vaccine's role in enhancing protection against L. infantum infections.