Association between endothelial function and autonomic modulation in patients with Chagas disease.

Background: Under homeostatic condition, the autonomic nervous system (ANS), through the release of vasoconstrictor neurotransmitters, and the endothelium, through the release of vasodilating substances, interact to maintain blood vessel tone. However, the association between those two systems in patients with Chagas disease in its indeterminate phase (IChD) has not been studied.

Objective: To assess the association between autonomic modulation parameters and endothelial function in patients with IChD.