Publications by authors named "Adrian Plaza-Diaz"

Article Synopsis
  • - The study analyzes the prevalence of benzodiazepine prescriptions among elderly patients visiting emergency departments in Spain and their impact on short-term health outcomes.
  • - Out of 25,557 patients studied, 30.8% were prescribed benzodiazepines, which were linked to an increased chance of returning to the emergency department but not to higher rates of hospitalization or mortality within 30 days.
  • - The findings suggest that while benzodiazepine use may lead to more frequent ED visits, it does not significantly affect hospitalization rates or mortality in the short term.
View Article and Find Full Text PDF

(1) Background: Knowledge about the behavior of antibiotics in critically ill patients has been increasing in recent years. Some studies have concluded that a high percentage may be outside the therapeutic range. The most likely cause of this is the pharmacokinetic variability of critically ill patients, but it is not clear which factors have the greatest impact.

View Article and Find Full Text PDF

The progressive aging and comorbidities of the population have led to an increase in the number of patients with polypharmacy attended to in the emergency department. Drug-related problems (DRPs) have become a major cause of admission to these units, as well as a high rate of short-term readmissions. Anticoagulants, antibiotics, antidiabetics, and opioids have been shown to be the most common drugs involved in this issue.

View Article and Find Full Text PDF

Introduction: Comparisons of Janus kinase inhibitors (JAKi) for treatment of rheumatoid arthritis in patients with inadequate response to biologic disease-modifying anti-rheumatic drugs are lacking. We assessed the relative efficacy and safety of four JAKi (tofacitinib, baricitinib, upadacitinib, and filgotinib) in this context.

Method: We performed an adjusted indirect comparison (IC) of randomized clinical trials using Bucher's method with an IC and mixed calculator.

View Article and Find Full Text PDF

Objectives: To evaluate the anticholinergic burden on discharge of patients treated for constipation in an emergency department (ED) and to assess the effect on emergency revisiting within 30 days.

Material And Methods: Observational retrospective cohort study. We collected cases with a discharge diagnosis of constipation after ED treatment between September 2018 and June 2019 and recorded information on all drugs taken and the anticholinergic burden of treatment.

View Article and Find Full Text PDF