Publications by authors named "Adrian Onken"

After cochlear implant (CI) insertion, there is a possibility of postoperative inflammation, which may involve proinflammatory markers such as interleukin-6. Detecting this inflammation promptly is crucial for administering anti-inflammatory drugs, if required. One potential method for detecting inflammation is using molecular imprinted polymers (MIPs).

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Article Synopsis
  • Researchers are developing a new method for detecting trace gases in the air using ionization energies, which can be miniaturized and fine-tuned.
  • Traditional methods for identification rely on large equipment, like mass spectrometers, but this new approach uses electron impact ionization, generated via the photoelectric effect, for better sensitivity at a lower scale.
  • The method achieves sensitivity levels of 1 ppm, comparable to classic photoionization detection (PID), and can identify substances with an accuracy of 30 meV, supported by quantum mechanical models.
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Delamination at heterogeneous material interfaces is one of the most prominent failure modes in active implantable medical devices (AIMDs). A well-known example of an AIMD is the cochlear implant (CI). In mechanical engineering, a multitude of testing procedures are known whose data can be used for detailed modeling with respect to digital twins.

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The ingress of body fluids or their constituents is one of the main causes of failure of active implantable medical devices (AIMDs). Progressive delamination takes its origin at the junctions where exposed electrodes and conductive pathways enter the implant interior. The description of this interface is considered challenging because electrochemically-diffusively coupled processes are involved.

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