The transcription factor MZF1 differentially regulates murine promoter variants linked to tumor susceptibility.

Mechanistic target of rapamycin (MTOR) is a highly conserved serine/threonine kinase that critically regulates cell growth, proliferation, differentiation, and survival. Previously, we have implicated as a plasmacytoma-resistance locus, , in mice. Here, we report that administration of the tumor-inducing agent pristane decreases gene expression to a greater extent in mesenteric lymph nodes of BALB/cAnPt mice than of DBA/2N mice.