Publications by authors named "Adrian K Ong"
Article Synopsis
- Dengue virus has four serotypes and is widespread in tropical regions, with no specific treatment or vaccine currently available, leading to challenges in understanding immune protection against the virus.
- Research indicates that serotype cross-reactive antibodies peak shortly after infection and decrease over about a year, complicating assessments of long-term immunity following dengue infections.
- A study found that secondary dengue patients produced antibodies specific to the virus's envelope protein more rapidly, suggesting that an E-specific ELISA is more effective for diagnosing secondary infections than traditional methods.
Background: The presentation of new influenza A(H1N1) is broad and evolving as it continues to affect different geographic locations and populations. To improve the accuracy of predicting influenza infection in an outpatient setting, we undertook a comparative analysis of H1N1(2009), seasonal influenza, and persons with acute respiratory illness (ARI) in an outpatient setting.
Methodology/principal Findings: Comparative analyses of one hundred non-matched cases each of PCR confirmed H1N1(2009), seasonal influenza, and ARI cases.
The long history of influenza drug development has both contributed practical advances in antiviral chemotherapy and improved the understanding of influenza pathogenesis and epidemiology. The role played by these antivirals continues to grow with the dual threats of seasonal and pandemic influenza. The neuraminidase inhibitors are proven effective for the chemoprophylaxis and treatment of influenza A and B, although early therapy is essential for disease mitigation.
View Article and Find Full Text PDFBackground: The Mycobacterium tuberculosis Beijing genotype is biologically different from other genotypes. We aimed to clinically and immunologically compare human tuberculosis caused by Beijing and non-Beijing strains.
Methods: Pulmonary tuberculosis patients were prospectively enrolled and grouped by their M.