Evaluating the Outcomes of Active Surveillance in Grade Group 2 Prostate Cancer: Prospective Results from the Canary PASS Cohort.

Purpose: Active surveillance (AS) for grade group (GG) 2 patients is not yet well defined. We sought to compare clinical outcomes of men with GG1 and GG2 prostate cancer undergoing AS in a large prospective North American cohort.

Materials And Methods: Participants were prospectively enrolled in an AS study with protocol-directed followup at 10 centers in the U.

Effect of Diagnostic Biopsy Practice Location on Grade/Volume Reclassification in Active Surveillance for Prostate Cancer: A Multicenter Analysis from the Canary PASS Cohort.

Introduction: We analyzed the Canary Prostate Cancer Active Surveillance (PASS) cohort to determine if patients who had diagnostic biopsy at an off-site practice were at higher risk of reclassification than those having their diagnostic biopsy at a PASS site.

Methods: Participants were prospectively enrolled at 10 academic institutions. We included patients with Gleason score 6 at diagnostic biopsy, <34% positive cores and a first surveillance biopsy in a PASS site <2 years after diagnosis.