Publications by authors named "Adrian Guevara"
Article Synopsis
- Chronic hand eczema (CHE) is a common skin condition that is hard to treat, but the drug dupilumab, known for treating atopic dermatitis, shows promise for CHE as well.
- A review of 22 studies involving 374 patients revealed that 80.3% experienced partial or complete improvement within 4-16 weeks of starting dupilumab, with effects often lasting beyond the studies.
- While dupilumab proved effective for various CHE subtypes, it was particularly successful for dyshidrotic and vesicular forms, but less so for hyperkeratotic eczema; the most common side effects included conjunctivitis and mild skin reactions.
Dermatitis herpetiformis (DH) is a chronic, pruritic, papulovesicular dermatosis on extensor surfaces that is characterized by a neutrophilic infiltrate and granular immunoglobulin A deposition at the dermal papillae. Although the presence of immunoglobulin A in the skin and the severity of DH are known to be associated with gluten intake, few drugs have been implicated in the induction of DH. We report a case of DH triggered by intramuscular injections of leuprolide acetate, a gonadotropin-releasing hormone analog, in a patient with a history of prostate cancer.
View Article and Find Full Text PDFObjective: To assess the preventive effect of a cyclooxygenase 2 inhibitor, celecoxib (Celebrex; G.D. Searle & Co, Skokie, Ill), in UV-induced skin cancer in hairless mice.
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