Intradermal testing of iodinated contrast media: Should we test up to pure or with diluted compounds only?

Background: Intradermal testing (IDT) with iodinated contrast media (ICMs) is an established diagnostic tool in patients with ICM hypersensitivity. Currently, it is unclear which test concentration is the more useful one, up to pure or up to 1:10 diluted ICMs.

Methods: We searched the literature database PubMed for eligible papers dealing with ICM allergy and their IDT results.

Cross-reactivity among iodinated contrast agents: should we be concerned?

Background: Although several papers deal with "cross-reactivity" in patients with iodinated contrast medium (ICM) hypersensitivity reactions (HSRs), there is no in-depth knowledge of this phenomenon. To define ICM-groups as potential reaction partners and to identify any potential clinical relevance in patients with ICM-HSRs.

Methods: The literature database PubMed was searched for eligible papers dealing with ICM-allergy and "cross-reactivity".