Correlation between PD-L1 expression and gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver.

Non-small cell lung cancers (NSCLC) are the most common type of lung cancer and can be classified according to the presence of mutually exclusive oncogenic drivers. The majority of NSCLC patients present a non-actionable oncogenic driver, and treatment resistance through the amplification of the () or the expression of programmed cell death protein 1 ligand (PD-L1) is common. Herein, we investigated the relation between gene amplification and PD-L1 expression in patients with advanced NSCLC and no other actionable oncogenic driver (i.