Persistent Gastrointestinal Bleeding after Aortic Valve Replacement in Heyde's Syndrome.

Heyde's syndrome (HS) represents an association between aortic stenosis and intestinal angiodysplasias, and it has been demonstrated that acquired von Willebrand disease plays a pivotal role in the pathophysiology of this syndrome. In patients with HS, von Willebrand factor deficiency represents an additional risk factor, further contributing to the risk of bleeding and anemia. We present the case of an 86-year-old patient diagnosed with HS and von Willebrand deficiency in 2018.

Distinct Features of Vascular Diseases in COVID-19.

The Coronavirus Disease 2019 (COVID-19) pandemic was declared in early 2020 after several unexplained pneumonia cases were first reported in Wuhan, China, and subsequently in other parts of the world. Commonly, the disease comprises several clinical features, including high temperature, dry cough, shortness of breath, and hypoxia, associated with findings of interstitial pneumonia on chest X-ray and computer tomography. Nevertheless, severe forms of acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) are not limited to the respiratory tract but also may be extended to other systems, including the cardiovascular system.

Severe Intentional Corrosive (Nitric Acid) Acute Poisoning: A Case Report and Literature Review.

Despite being one of the most debilitating conditions encountered in the field of toxicology, there is a lack of neutralization measures for the toxins involved in acute corrosive poisoning, and this promotes progressive contact injury of deep tissues after poisoning has occurred. Multiple controversies still surround management strategies during the acute phase of poisoning and the long-term follow-up of the patient. Here, we report a severe case of intentional poisoning with nitric acid complicated by extensive injury of the upper digestive tract, multiple stricture formation, and complete dysphagia.

Native and Prosthetic Simultaneously Double Valve Infective Endocarditis with -Case-Based Review.

Infective endocarditis is a severe infective heart disease, commonly involving native or prosthetic valves. It frequently presents with univalvular involvement and simultaneous double valve or multivalvular involvement is rarely described. The third leading cause of infective endocarditis worldwide is , which is associated with high mortality rates despite important advances in antimicrobial therapy.

Management of Hyponatremia in Heart Failure: Practical Considerations.

Hyponatremia is commonly encountered in the setting of heart failure, especially in decompensated, fluid-overloaded patients. The pathophysiology of hyponatremia in patients with heart failure is complex, including numerous mechanisms: increased activity of the sympathetic nervous system and the renin-angiotensin-aldosterone system, high levels of arginine vasopressin and diuretic use. Symptoms are usually mild but hyponatremic encephalopathy can occur if there is an acute decrease in serum sodium levels.

Recognition and Management of Serotonin Toxidrome in the Emergency Department-Case Based Review.

Serotonin syndrome (SS) is a clinical toxidrome with high variability in clinical practice. It develops due to increased serotonin levels in the central nervous system. With an underestimated frequency, SS can develop following an overdose, a therapeutic dose increase, or drug to drug interaction of at least one serotonergic agent.

The Value of Early and Follow-Up Elevated Scores Based on Peripheral Complete Blood Cell Count for Predicting Adverse Outcomes in COVID-19 Patients.

Background: The ongoing COVID-19 pandemic has put a constant strain on hospital resources, so there is a dire need for investigation methods that are widely available and that can predict mortality and the need for critical care. Hematological indices, which can be easily calculated from a complete blood count (CBC), are useful in determining a patient’s inflammatory response to infectious diseases. Aim: This was a prospective cohort study that aimed to assess the prognostic value of scores based on CBCs in hospitalized patients with mild or moderate COVID-19 and medical comorbidities regarding the need for intensive care unit (ICU) therapy and short-term mortality.

Inflammatory and Cardiac Biomarkers in Relation with Post-Acute COVID-19 and Mortality: What We Know after Successive Pandemic Waves.

Background: Biomarkers were correlated with mortality in critically ill COVID-19 patients. No prediction tools exist for noncritically ill COVID-19 patients. We aimed to compare the independent prognostic value of inflammation and cardiac biomarkers for post-acute COVID-19 patients and the 30-day mortality rate in noncritically ill COVID-19 patients, as well as the relation with the virus variant involved.

From chronic pruritus to neuroendocrine tumor: A case report.

Chronic pruritus is a major and distressing symptom of many diseases of dermatological, neurological, psychogenic or systemic origin. This chronic itch could be a presenting sign of malignancy; therefore, paraneoplastic pruritus has also been associated with neuroendocrine tumors (NETs). This article focuses on a patient presenting with chronic pruritus for the past 12 months and who received numerous treatment schemes with very poor clinical improvement, that presented in the hospital for worsening of the chronic pruritus associated with skin rash and significant weight loss (approximately 6 kg over a 2-month period).

Acute Clinical Syndromes and Suspicion of SARS-CoV-2 Infection: The Experience of a Single Romanian Center in the Early Pandemic Period.

: During the coronavirus disease 2019 (COVID-19) pandemic, patients with chronic diseases suffering exacerbations have required acute medical care. The purpose of our study was to determine useful criteria for the differentiation of patients with acute clinical syndromes and suspicion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. : This was an observational retrospective study, conducted in an internal medicine clinic from April to May 2020.

Epidemiological study of metabolic syndrome and risk of diabetes mellitus in a rural family medicine practice in Bacau County.

Aim: This descriptive epidemiological study included 615 subjects investigated by their family doctor in the interval October 2011- August 2012.

Material And Methods: Patients were selected according to 2012 IDF diagnostic criteria resulting 304 patients.

Results: There was a Gaussian distribution of waist circumference (WC) with a maximum in age-group 70-80 years (46.

Epidemiology of B/C virus infection hepatitis in the Northern Moldavian correctional facilities risk factors.

Aim: To identify the specific risk factors for chronic hepatitis B/C virus infections in the correctional system in Moldova (Romania).

Material And Methods: The study included 533 subjects imprisoned in three correctional facilities located in the Northern region of Moldova. The subjects were divided into 2 groups: HBV/HBC group--108; Control group--425.

Stress: from symptom to disease.

Aim: To evaluate the presence and role of stress in causing diseases.

Materials And Methods: We conducted a 6-month study in patients who presented for the first time with a series of symptom and tried to look for an organic cause of those symptoms. We wanted to see the impact of stress in everyday life and its role in causing various diseases.

[Causes of functional digestive disorders and therapeutic approach in primary care medicine].

Unlabelled: Functional diseases of digestive tract are an ubiquitary problem of diagnosis and treatment for ambulatory care services. Its evolution is chronicle but there are no organic lesions for the beginning. Nevertheless, it impairs quality of life and creates many days of incapacity of work.

[Obesity prevention--is there any limits for primary care medicine].

What does obesity mean? One of the people's health markers is the nutritional steady-state, the mean ponderal equilibrium. The normal weight means the longest life expectancy assuring body weight, from all points of view. The body weight increasing means adipose tissue accumulation and the onset of obesity.

[Metabolic syndrome and breast cancer risk in post-menopausal women].

Unlabelled: Lipid metabolism disorders--breast cancer risk association in postmenopausal women was searched in many studies; the HDL-cholesterol value triggered most of controversies. Some authors plead for increased breast cancer risk in overweight/obese postmenopausal women if HDL is higher while others plead for higher risk if HDL is lower then in general population.

Material And Method: We studied a 110 subjects female population aged between 41 and 69, and determined height, weight, body mass index (BMI), abdominal perimeter (AP), lipid parameters (total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides).

[Android obesity and breast cancer risk].

Unlabelled: The 1998 report on the occasion of the 4th anniversary of International obesity Task Force emphasized that overweight (BMI > 25) is also linked to the increasing incidence of some neoplasias--breast, colon, endometer, prostate or kidney. Carmichael and Bates showed an inverse relationship between BMI and perimenopausal breast cancer.

Material And Method: We studied a group of 110 patients divided in three subgroups--30 patients who had just been diagnosed with breast cancer; 50 patients with breast dysplasia diagnosed by mammography and mammary echography; 30 patients with no modifications on mammography or breast echography.

[Dietary survey in an obese population].

The body mass index (BMI) shows a rate of 17.4% patients suffering from first degree fatness and 56.5% from second degree fatness.

[Importance of mild dyslipidemias determining the cardio-vascular risk factors].

The aim of our study was to correlate "medium" dyslipidemias with cardio-vascular diseases, especially essential hypertension (EHT). We selected 488 cases using randomization, from a population of hypertensive people. About 210 cases benefited by lipidograms and risk assessment, using special diagrams.

[Obesity prevalence in Iaşi county].

Unlabelled: Our study is a part of a national study initiated by ARSO (Romanian Association for Study of Obesity). We selected a statistically representative sample (1500 cases). Study was built upon a questionnaire, made by primary care physicians.