Cerebral activities were measured during 21 essions in NeurOptimal (NO)-trained patients with bruxism. Salivary cortisol levels were quantified for each six training sessions (session 1, 6, 12, 18, 21) in 12 patients with bruxism after performing their pre- and post-NeurOptimal sessions. Their cortisol levels were compared with controls (without stress).
View Article and Find Full Text PDFBiomolecules
February 2020
Background: Contextual fear conditioning (CFC) is a rodent model that induces a high and long-lasting level of conditioning associated with traumatic memory formation; this behavioral paradigm resembles many characteristics of posttraumatic stress disorder (PSTD). Chemokines (chemotactic cytokines) play a known role in neuronal migration and neurodegeneration but their role in cognition is not totally elucidated.
Aim: We ascertain whether CCR5/RANTES beta chemokines (hippocampus/prefrontal cortex) could play a role in fear memory consolidation (CFC paradigm).
Titanium is the mean biocompatible metal found in dental titanium alloys (Ti-6Al-4V). The safety of certain dental biomaterial amalgams has been questioned in patients. The levels of several systemic cytokines (interleukin (IL)-1 beta, IL-4: pg/mL) and chemokines (monocyte chemoattractant protein-1 (MCP-1), soluble fractalkine (CX3CL1: pg/mL) were determined using ELISA and compared between these study groups.
View Article and Find Full Text PDFAntioxidants (Basel)
April 2019
The toxicity of heavy metals such as Hg is a serious risk for human health. We evaluated whether 90 days of nutritional supplementation (d90, = 16) with (CV) and extracts in conjunction with aminosulphurate (nutraceuticals) supplementation could detox heavy metal levels in patients with long-term titanium dental implants (average: three, average: 12 years in mouth) and/or amalgam fillings (average: four, average: 15 years) compared to baseline levels (d0: before any supplementation, = 16) and untreated controls (without dental materials) of similar age (control, = 21). In this study, we compared levels of several heavy metals/oligoelements in these patients after 90 days ( = 16) of nutritional supplementation with CV and aminozuphrates extract with their own baseline levels (d0, = 16) and untreated controls ( = 21); 16 patients averaging 44 age years old with long-term dental amalgams and titanium implants for at least 10 years (average: 12 years) were recruited, as well as 21 non-supplemented controls (without dental materials) of similar age.
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