Publications by authors named "Adolfo Marcelo Nique"

Article Synopsis
  • Research conducted on 3,400 febrile patients in Peru between 2020-2021 revealed a positive case of Rio Mamore hantavirus, highlighting the endemic presence of this virus in the region.
  • Genetic analysis showed a strong similarity to past rodent-associated hantavirus cases from Loreto, indicating ongoing circulation.
  • Findings suggest the need for enhanced hantavirus diagnostics and surveillance in Peru and Latin America due to the detection of multiple distinct hantavirus strains.
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During early 2021, Peru had the highest COVID-19-associated per-capita mortality rate. Socioeconomic inequality, insufficiently prepared healthcare, and surveillance systems are factors explaining the mortality rate, which can be severely worsened by early undetected SARS-CoV-2 circulation. We tested 1,441 individuals with fever sampled during August 2019-May 2021, several months before the first SARS-CoV-2 seroprevalence study available so far in Lima, Peru, for SARS-CoV-2-specific antibodies.

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One of the biggest challenges during the pandemic has been obtaining and maintaining critical material to conduct the increasing demand for molecular tests. Sometimes, the lack of suppliers and the global shortage of these reagents, a consequence of the high demand, make it difficult to detect and diagnose patients with suspected SARS-CoV-2 infection, negatively impacting the control of virus spread. Many alternatives have enabled the continuous processing of samples and have presented a decrease in time and cost.

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Objectives.: To design and assess a multiepitopic protein as a candidate for a vaccine against Carrion disease.

Materials And Methods.

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