Loss of P16 Protein Expression and Its Association with Epstein-Barr Virus LMP-1 Expression in Hodgkin's Lymphoma.

Background: Expression of Epstein-Barr virus Latent Member Protein-1 (EBV LMP-1) and loss of P16 protein expression are documented in lymphoma, indicating a relationship between them, but this relationship is not clear and sometimes contradictory. Thus, this study was conducted to examine the relationship between the loss of P16 and EBV LMP-1 expression in Jordanian patients diagnosed with lymphoma.

Methods: Sections were made from archival formalin-fixed and paraffin-embedded blocks from 55 patients diagnosed with lymphoma.

African Jordanian population genetic database on fifteen short tandem repeat genetic loci.

Aim: To establish a genetic database of the African-Jordanian population for forensic and paternity testing purposes.

Method: Allelic distribution at fifteen short tandem repeat (STR) loci was determined for 95 healthy unrelated African-Jordanians. The 15 autosomal STR loci, included within the GenePrint PowerPlex 16 system, were amplified from the subset of the 95 DNA extracts isolated from the population sample.

Jordanian population data on five STR forensic loci: D16S539, TPOX, CSF1PO, Penta D, and Penta E.

The allele distributions at five STR loci, D16S539, TPOX, CSF1PO, Penta D, and Penta E have been determined. None of the five loci were found to deviate from Hardy-Weinberg expectations according to the results of the G (homogeneity) test.