Rapid urbanization attributed to population growth is affecting the built environment's thermal and landscape dynamics. Using Landsat satellite datasets, this study investigated the complex interplay between urban Land Cover (LC) modification, fluctuation in Land Surface Temperature (LST) and severity of Urban Heat Island (UHI) from 1990 to 2020 in Peshawar City, Pakistan. Thermal bands were used to calculate LST and severity of UHI using the Urban Thermal Field Variance Index (UTFVI).
View Article and Find Full Text PDFBackground: Copper oxide (CuO) nanoparticles (CO NPs) are in extensive use during our everyday life as antimicrobial agent, lubricant, in manufacturing electrodes of lithium ion batteries as well as for photo catalytic degradation of organic pollutants. Due to extensive and diverse use CuO NPs, they are likely to accumulate in the environment and to affect the live forms. Present investigation was aimed to report the biocompatibility of CO NPs in Wistar rats in sex specific manner.
View Article and Find Full Text PDFObjective: Dostarlimab, a humanized monoclonal PD-1 blocking antibody, is being tested as a cancer therapy in this review. Specifically, it addresses mismatch repair failure in endometrial cancer and locally progressed rectal cancer patients.
Data Sources: A thorough database search found Dostarlimab clinical trials and studies.
Introduction Meniscus tear is a commonly encountered sports-related injury requiring surgical intervention due to knee mobility dysfunction and discomfort. Previously, it has been thought that these are non-functional vestigial structures and they used to be excised commonly. Recent studies have shown that meniscal repair gives superior results when compared with partial meniscectomy.
View Article and Find Full Text PDFMicro-expressions (ME) are rapidly occurring expressions that reveal the true emotions that a human being is trying to hide, cover, or suppress. These expressions, which reveal a person's actual feelings, have a broad spectrum of applications in public safety and clinical diagnosis. This study provides a comprehensive review of the area of ME recognition.
View Article and Find Full Text PDFMasson's tumor, also named intravascular papillary endothelial hyperplasia (IPEH), is a rare, benign vascular tumor. Evaluation by clinical features can be confused with other soft tissue tumors. Therefore, the diagnosis should be confirmed by histopathological examination.
View Article and Find Full Text PDFRationale: Congenital adrenal hyperplasia (CAH) is considered one of the most common inherited disorders. In about more than 95% of all CAH cases, the deficient enzyme is 21-hydroxylase. Infertility is an important complication of this disease, and although this topic has been studied more frequently in females, cases, and literature reviews of the causes of infertility in male patients are constantly increasing.
View Article and Find Full Text PDFThe present research aimed to fractionate L. (XSL) foliage phenolics into a set of solvents and evaluate their antioxidant potential and anti-diabetic activity against Alloxan monohydrate-induced diabetic mice. For this purpose, XSL foliage was fractionated into petroleum ether, ethyl acetate, ethanol, and water orbital type shaking and tested for the presence of phenolics, and their antioxidant and antidiabetic potential.
View Article and Find Full Text PDFIn the current study, whey protein-based nanofibers were fabricated to encapsulate . Purposely, different ratios of PVA (polyvinyl alcohol) and WPI (whey protein isolate) were blended to fabricate nanofibers. Nanofiber mats were characterized in terms of particle size, diameter, tensile strength, elongation at break, and loading efficiency.
View Article and Find Full Text PDFObjectives: To compare the efficacy of topical Nepafenac 0.1 % and Diclofenac 0.1% eye drops in reducing the aqueous cells in the anterior chamber in an un-eventful post cataract surgery.
View Article and Find Full Text PDFBackground: Breast cancer is the most common malignancy among women worldwide. We aimed to know the past trends of age-specific breast cancer incidence rates in Faisalabad city.
Methods: A retrospective study was designed at Allied Hospital Faisalabad (AHF), Pakistan from 2014-2018.
Objective: To assess the efficacy of topical azithromycin drops versus oral doxycycline therapy in meibomian gland dysfunction.
Methods: The prospective randomised trial was conducted from December 2019 to June 2020 at the Qazi Hussain Ahmad Medical Complex, Nowshera, Pakistan, and comprised patients of either gender aged 26-42 years having long-standing posterior blepharitis / meibomian gland dysfunction. The subjects were randomised into two equal groups.
Nanoscale surface roughness has conventionally been induced by using complicated approaches; however, the homogeneity of superhydrophobic surface and hazardous pollutants continue to have existing challenges that require a solution. As a prospective solution, a novel bubbled-structured silica nanoparticle (SiO) decorated electrospun polyurethane (PU) nanofibrous membrane (SiO@PU-NFs) was prepared through a synchronized electrospinning and electrospraying process. The SiO@PU-NFs nanofibrous membrane exhibited a nanoscale hierarchical surface roughness, attributed to excellent superhydrophobicity.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
July 2023
Intra-vitreal Vancomycin (IV-V) and ceftazidime (IV-C) are commonly in the treatment of acute post operative endophthalmitis. But there are suboptimal responses in some cases due to the emergence of antibiotic resistant micro-organisms. Moxifloxacin is a wide range antibacterial drug that is available as an eye drops for topical use for different types of ocular infections including post-operative endophthalmitis.
View Article and Find Full Text PDFNanofiber-based facial masks have attracted the attention of modern cosmetic applications due to their controlled drug release, biocompatibility, and better efficiency. In this work, extract incorporated electrospun polyvinyl alcohol (PVA) nanofiber membrane was prepared to obtain a sustainable and hydrophilic facial mask. The electrospun incorporated PVA nanofiber membranes were characterized by scanning electron microscope, Ultraviolet-visible spectroscopy (UV-Vis) drug release, water absorption analysis, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging, and antibacterial activity (qualitative and quantitative) at different PVA and concentrations.
View Article and Find Full Text PDFSweat is a natural body excretion produced by skin glands, and the body cools itself by releasing salty sweat. Wetness in the underarms and feet for long durations causes itchiness and an unpleasant smell. Skin-friendly reusable sweat pads could be used to absorb sweat.
View Article and Find Full Text PDFComput Med Imaging Graph
January 2023
Artifacts are a common occurrence in Diffusion MRI (dMRI) scans. Identifying and removing them is essential to ensure the accuracy and viability of any post-processing carried out on these scans. This makes quality control (QC) a crucial first step prior to any analysis of dMRI data.
View Article and Find Full Text PDFTextile-supported nanocomposite as a scaffold has been extensively used in the medical field, mainly to give support to weak or harmed tissues. However, there are some challenges in fabricating the nanofiber/textile composite, i.e.
View Article and Find Full Text PDFSynthetic antibiotics have captured the market in recent years, but the side effects of these products are life-threatening. In recent times, researchers have focused their research on natural-based products such as natural herbal oils, which are eco-friendly, biocompatible, biodegradable, and antibacterial. In this study, polyethylene oxide (PEO) and aqueous ginger extract (GE) were electrospun to produce novel antibacterial nanomembrane sheets as a function of PEO and GE concentrations.
View Article and Find Full Text PDFIn this study, ZIF-67-based mixed matrix membrane was synthesized with a solution casting method using tetrahydrofuran as the solvent. The as-synthesized ZIF-67 was characterized using PXRD, TGA, ATR-FTIR, and BET analysis for the surface area measurements. The minimum 3 wt% loading of ZIF-67 was incorporated within a hydrophobic polymer to evaluate the CO adsorption performance of ZIF-67.
View Article and Find Full Text PDFThe ineptitude of conventional water management systems to eradicate noxious compounds leads to the development of advanced treatment systems. The disclosure of graphene-based photocatalytic degradation for the eradication of phenolic compounds has become the "apple of the eye" for many researchers. This review article describes the advanced research progress during the period of 2008-2021 in graphene-based nanocomposites and discusses their different synthesis methods.
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