Optimisation and evaluation of extracted Karanjin loaded liposomal topical formulation for treatment of psoriasis in tape-stripped mouse model.

Aim: The present work is focus on development of anti-psoriasis activity of Karanjin (isolated from seed oil) loaded liposome based lotion for enhancement of skin permeation and retention.

Method: Karanjin was isolated using liquid-liquid extraction method and characterised by HPLC analysis and partition coefficient. Further, isolated Karanjin was loaded into liposomes using thin-film hydration technique and optimised by Box-Behnken design.

Natural and synthetic agents for the treatment of Sarcoptes scabiei: a review.

Sarcoptes scabiei is an ectoparasite known to infect different species of mammals. Mite is known to infect mankind since antiquity. Current scabicidal agents are becoming less effective due to resistance generated by the mite.