Biomimetic remineralization of eroded dentin by synergistic effect of calcium phosphate and plant-based biomodifying agents: An study.

Context: Dentin, due to its organic content, exhibits a high susceptibility to dental erosion owing to its high permeability to intrinsic acids. A crucial challenge for successful remineralization of demineralized dentin is reestablishing a complete spatial relationship between the mineral and collagen.

Aims: This study aimed to evaluate the synergistic effect of casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACPF) with plant-based dentin biomodifying agents: Grape seed extract (GSE), green tea extract (GTE), and cranberry extract (CE) on biomimetic remineralization of eroded dentin.