Publications by authors named "Aditya S Deshpande"
Article Synopsis
- - The researchers developed a new method called Pore-C, which combines chromatin conformation capture with nanopore sequencing to study high-order 3D interactions among genomic loci across the genomes of human cell lines.
- - They created a statistical tool named Chromunity to identify 'synergies', or sets of genomic loci that have an increased frequency of high-order contacts, particularly in active chromatin regions like enhancers and promoters.
- - Applying these techniques revealed that such high-order interactions are vital for gene regulation in various contexts, including prostate and breast cancer, highlighting the link between 3D genome structure and lineage-specific transcriptional programs.
We present here a case of tissue destruction and paresthesia following the accidental injection of sodium hypochlorite instead of local anesthetic in a patient scheduled for endodontic procedure. The accident was managed by the local injection of steroid, debridement of necrotic tissue, daily dressings and medications. Wound healing was satisfactory at the end of 1 month.
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