Association between Oral Cancer and Smokeless Tobacco Use in Rural Indian Men: A Prospective Cohort Study.

Background: Smokeless tobacco (SLT) use, particularly gutka and khaini, is a significant public health concern in India, mainly in rural areas. This prospective cohort study aimed to investigate the association between SLT use and oral cancer incidence among rural Indian men.

Methods: A cohort of 300 rural Indian men without a history of oral cancer was recruited and followed for five years.