Publications by authors named "Adinda D Azhar"
Article Synopsis
- Cynomolgus macaques are vital for biomedical research, especially in studying geriatric diseases, but socially housing sexually mature males presents challenges due to potential aggression, particularly with those previously kept alone.
- This paper details a 2.5-year experience at IPB University, focusing on successfully housing young adult males and the difficulties encountered while trying to group older males aged over 15 years, using temperament assessments for pairing.
- The research concluded that older males are best housed in pairs or triads determined by their temperament and dominance, highlighting the importance of behavior assessments and veterinary management in these social housing efforts.
There is a critical need to generate age- and sex-specific survival curves to characterize chronological aging consistently across nonhuman primates (NHP) used in biomedical research. Sex-specific Kaplan-Meier survival curves were computed in 12 translational aging models: baboon, bonnet macaque, chimpanzee, common marmoset, coppery titi monkey, cotton-top tamarin, cynomolgus macaque, Japanese macaque, pigtail macaque, rhesus macaque, squirrel monkey, and vervet/African green. After employing strict inclusion criteria, primary results are based on 12,269 NHPs that survived to adulthood and died of natural/health-related causes.
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- There is a significant need to create age- and sex-specific survival curves for nonhuman primates (NHP) in biomedical research to better understand aging.
- A study analyzed data from over 110,000 captive NHP to generate survival curves for various species, reporting meaningful differences in lifespans and health based on sex and species type.
- Results indicated that male NHP, particularly among certain African and Asian species, had reduced survival rates, and median lifespans were often lower than what was previously documented, suggesting these analyses may more accurately reflect healthspan rather than just lifespan.