Clinical challenges of SARS-CoV-2 variants (Review).

Since the first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, there have been challenges recognizing the clinical features of SARS-CoV-2 and identifying therapeutic options. This has been compounded by viral mutations that affect clinical response and primary epidemiological indicators. Multiple variants of SARS-CoV-2 have been identified and classified on the basis of nomenclature implemented by scientific organizations and the World Health Organisation (WHO).

Respiratory rehabilitation in healing depression and anxiety in COPD patients.

Unlabelled: Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory affection of the whole lung, characterized by an accelerated loss of the pulmonary functions, that reduces the patients' independence and stops them from having a normal, active life. The medical rehabilitation is considered "Third class rehabilitation", after preventive medicine and pharmaceutical medicine, and the respiratory rehabilitation recovery represents a complex structure of service addressing to patients with chronic pulmonary illnesses whose aim is to optimize the physical performances, psycho-social and autonomy.

Aim And Objectives: The main objective of this study is to show the importance of respiratory rehabilitation that is correctly and timely made, based on the gravity and stage of the illness, the COPD patient's associated illnesses and their importance in improving the patient's mental and physical quality of life.

Bronchiectasis in cystic fibrosis and pregnancy.

Cystic fibrosis is an autosomal recessive disease with a prognosis determined by the extent of pulmonary lesions. Here we present a rare case of a patient diagnosed with cystic fibrosis in the pediatric service, but who came for the first time to the Pneumology Hospital of Iasi. Respiratory failure, recurrent pulmonary infections and associated metabolic modifications generate a high vital risk during pregnancy.

Chronic venous insufficiency stage v ceap secondary to hereditary thrombophilia at a young man.

Hereditary thrombophilia is a rare disease of general population, which is responsible for debilitating consequences in severe cases. We present the case of a young male patient whose pathology and symptoms occurred since the age of two, which determined a venous insufficiency stage V with important limitation of the locomotors ability and plenty of complications. The aim of this paper is to draw attention to a disease that sometimes is not diagnosed on a first visit to the doctor.

[Non-cystic bronchiectasis: pathogenic correlations between the parameters of body composition, systemic inflammation and respiratory function].

Unlabelled: The causes of bronchiectasis may be idiopathic or secondary to pulmonary diseases. The consequences determined by this pathology are found on different levels.

Aim: To determine the relationships between the parameters of body mass composition, chronic systemic inflammatory syndrome and lung function inpatients with bronchiectasis.

[Pathophysiology and treatment of bronchectasis].

Bronchiectasis is a complex pathology which consists of some important morphopathological changes in the lumen of the bronchi that consecutively determines recurrent pulmonary infections with a diversity of germs. The repeated episodes of infection are associated with chronic colonization of the respiratory system with certain pathogen microorganisms and play an important role in the maintenance of the chronic inflammatory syndrome, as well as the decline of the pulmonary function. This chronic inflammation is represented by a series of fisiopathological changes (the raised number of neutrophiles, macrophages, alteration in the expression of pro-inflammatory cytokine and adhesion molecules).