Publications by authors named "Adina Mariana Ghemigian"
Pathogenesis and Management Strategies in Radioiodine-Refractory Differentiated Thyroid Cancer: From Molecular Mechanisms Toward Therapeutic Approaches: A Comprehensive Review.
Iulia-Alexandra Voinea Eugenia Petrova Nicoleta Dumitru Andra Cocoloș Dumitru Ioachim Adina Mariana Ghemigian
J Clin Med
November 2024
Thyroid cancer (TC) remains the most common cancer in endocrinology. Differentiated thyroid cancer (DTC), the most common type of TC, generally has a favorable outlook with conventional treatment, which typically includes surgery along with radioiodine (RAI) therapy and thyroid-stimulating hormone (TSH) suppression through thyroid hormone therapy. However, a small subset of patients (less than 5%) develop resistance to RAI.
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- - Cortisol plays a crucial role during acute stress, but some COVID-19 patients experience low levels due to damage to the pituitary and adrenal glands, leading to adrenal insufficiency that often necessitates glucocorticoid treatment.
- - The review examines 84 cases of adrenal insufficiency associated with COVID-19, drawing from various studies and post-mortem analyses, emphasizing the importance of histopathological and imaging findings for accurate diagnosis.
- - Adrenal damage can be linked to several factors, including blood clots and coagulation issues, as well as the severe multiorgan impact of COVID-19, resulting in a wide spectrum of symptoms from severe adrenal crisis to mild or asymptomatic presentations.
Phyllodes tumors (PTs) are rare tumors of the breast, which encompass both stromal and epithelial components. The maximum incidence is in the fourth decade of life. Most of these tumors are benign, but about one third can be malignant acting as sarcomas.
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