Publications by authors named "Adila Aili"

Background: Noninvasive mechanical ventilation (NIV) is recommended as the initial mode of ventilation to treat acute respiratory failure in patients with AECOPD. The Noninvasive Ventilation Outcomes (NIVO) score has been proposed to evaluate the prognosis in patients with AECOPD requiring assisted NIV. However, it is not validated in Chinese patients.

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  • The study examined characteristics, treatments, and clinical outcomes of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in China, highlighting a need for more research on sex differences.
  • A total of 14,007 AECOPD patients were analyzed, with females generally older and having more comorbidities, while also showing differences in treatment such as higher rates of ICU admission and antibiotic use compared to males.
  • Despite these clinical differences, the overall in-hospital and long-term mortality rates were similar for both sexes, although female smokers had significantly higher in-hospital mortality compared to their male counterparts.
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  • A study investigated the high mortality rates among hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and cardiovascular diseases (CVDs) to create a new risk score for predicting mortality.
  • Using data from a large cohort, researchers developed the ABCDMP score, which includes key patient factors such as age, blood urea nitrogen levels, and vital signs to assess risk.
  • The ABCDMP score demonstrated strong predictive power, outperforming existing risk scores, and can help guide treatment decisions and future clinical research for these patients.
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  • High blood urea nitrogen (BUN) levels are observed in some patients with acute exacerbation of COPD (AECOPD) and may correlate with worse clinical outcomes, though past research has yielded mixed results.
  • A study analyzed data from 13,431 AECOPD patients, finding that those who did not survive had significantly higher BUN levels (9.5 vs 5.6 mmol/L), establishing a BUN cutoff of 7.30 mmol/L as a predictor of in-hospital mortality.
  • The findings indicate that elevated BUN is an independent risk factor for both in-hospital mortality and the need for intensive care, suggesting it could help in identifying and managing high-risk AECOPD patients.
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To study the clinical features and related factors of invasive pulmonary aspergillosis (IPA) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This retrospective study enrolled patients hospitalized for AECOPD in ten tertiary hospitals of China from September 2017 to July 2021. AECOPD patients with IPA were included as case group, AECOPD patients without IPA were randomly selected as control group from the same hospitals and same hospitalization period as the patients with IPA using the random function in the software of Microsoft Excel 2003, at a ratio of 2∶1.

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  • The study investigates the prognostic significance of diastolic blood pressure (DBP) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) to identify its relationship with negative health outcomes.
  • A total of 13,633 AECOPD patients were examined, revealing that low DBP (<70 mmHg) on admission significantly increased the risk of in-hospital mortality, need for invasive mechanical ventilation, and ICU admission.
  • The research indicates that as DBP decreases, the risk of mortality rises, highlighting the importance of monitoring DBP in AECOPD patients upon hospital admission.
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Purpose: The prognostic value of blood eosinophils in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) remains controversial. This study aimed to evaluate whether blood eosinophils could predict in-hospital mortality and other adverse outcomes in inpatients with AECOPD.

Methods: The patients hospitalized for AECOPD were prospectively enrolled from ten medical centers in China.

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Purpose: Recurrent laryngeal nerve (RLN) invasion by extranodal extension (ENE) is a rare condition that may occur in papillary thyroid cancer (PTC), and it has never been characterised in the literature.Our research aims to investigate the clinical significance of ENE to RLN including its effect on vocal cord function, relationship with the aggressive behaviour of PTC, and optimal surgical methods.

Methods: A total of 3119 patients, including 2868 patients without RLN invasion, 251 patients with RLN invasion [categorised into the ENE invasion group (n = 55) and extrathyroidal extension (ETE) invasion group (n = 196)] were analyzed retrospectively.

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  • - The study aimed to determine if D-dimer levels can effectively predict the risk of venous thromboembolism (VTE) in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), comparing it to the Padua Prediction Score (PPS).
  • - Researchers enrolled 4,468 AECOPD patients from seven medical centers, finding that 2.01% developed VTE within two months; results showed D-dimer had a significantly higher predictive value than PPS for VTE risk.
  • - The study concluded that D-dimer is a more reliable tool for predicting VTE than PPS, suggesting its use could improve thromboprophylaxis strategies in patients with AECOPD
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To explore the association between syncope and poor prognosis and related factors of syncope in patients with acute pulmonary embolism (APE). A total of 740 patients with first diagnosed APE treated in West China Hospital of Sichuan University from September 1, 2016 to December 30, 2019 were enrolled. The basic information and clinical information (including clinical manifestations, complications, auxiliary examination, treatment and prognosis, etc.

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BACKGROUND Infection with Echinococcus granulosus is endemic in sheep and dogs in Central Asia, including Tibet. In humans, ingested parasites from the gastrointestinal system enter the liver via the portal vein. Rarely, hepatic hydatid cysts can rupture into the portal vein and embolize to the lungs.

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Background:  Inpatients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are at increased risk for venous thromboembolism (VTE); however, the prophylaxis for VTE is largely underused in China. Identifying high-risk patients requiring thromboprophylaxis is critical to reduce the mortality and morbidity associated with VTE. This study aimed to evaluate and compare the validities of the Padua Prediction Score and Caprini risk assessment model (RAM) in predicting the risk of VTE in inpatients with AECOPD in China.

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Background: Pleural effusion is observed in a subset of patients with acute pulmonary embolism (APE) and may be linked to clinical outcome, but findings from previous studies have been inconsistent. This study aimed to investigate the prevalence and clinical significance of pleural effusion in Chinese patients with APE.

Methods: Clinical data from hospitalized patients with APE were retrospectively collected and the prevalence of pleural effusion was determined.

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