Development of a high throughput and low cost model for the study of semi-dry biofilms.

The persistence of microorganisms as biofilms on dry surfaces resistant to the usual terminal cleaning methods may pose an additional risk of transmission of infections. In this study, the Centre for Disease Control (CDC) dry biofilm model (DBM) was adapted into a microtiter plate format (Model 1) and replicated to create a novel model that replicates conditions commonly encountered in the healthcare environment (Model 2). Biofilms of grown in the two models were comparable to the biofilms of the CDC DBM in terms of recovered log CFU well.