Publications by authors named "Adigo Setargie Tsega"
Proc Natl Acad Sci U S A
August 2022
Article Synopsis
- Xylomyrocins are a new class of nonribosomal peptide metabolites found in specific fungi, identified using advanced techniques like HRMS/MS and gene mining.
- These compounds are characterized by a unique d-xylonic acid component, indicating a link between carbohydrate breakdown and peptide production.
- Structural variations among xylomyrocins arise from differences in amino acid composition, nucleophile selection for macrocyclic ester formation, and some unexpected methylation patterns despite the absence of specific methyltransferase domains.
