Meningitis retention syndrome (MRS) represents a rare condition in which there is meningitis accompanied by urinary retention in the absence of any other neurological symptoms. MRS is usually misdiagnosed as a urinary tract infection due to varied clinical symptoms. It is a self-limiting syndrome that often presents with prodromal symptoms of meningitis.
View Article and Find Full Text PDFAim The study aimed to evaluate the predictive factors that determined stone-free rate (SFR) after retrograde intrarenal surgery (RIRS). Materials and methods This prospective study was conducted on 183 patients undergoing RIRS for renal stones. Patients were categorized into two groups, depending on stone-free status one month following the procedure.
View Article and Find Full Text PDFObjective: The study aimed to identify the various risk factors for infective complications following retrograde intrarenal surgery (RIRS).
Materials And Methods: The study was conducted over one year, and the incidence of infectious complications after RIRS was calculated. Patients were divided into two groups based on the presence and absence of infective complications and were compared in terms of preoperative and operative characteristics.
Activation of the Wnt/β-catenin pathway regulates gene expression by promoting the formation of a β-catenin-T-cell factor (TCF) complex on target enhancers. In addition to TCFs, other transcription factors interact with the Wnt/β-catenin pathway at different levels to produce tissue-specific patterns of Wnt target gene expression. The transcription factor SOX9 potently represses many Wnt target genes by downregulating β-catenin protein levels.
View Article and Find Full Text PDFThere is a large gap between the deep understanding of mechanisms driving tumour growth and the reasons why patients ultimately die of cancer. It is now appreciated that interactions between the tumour and surrounding non-tumour (sometimes referred to as host) cells play critical roles in mortality as well as tumour progression, but much remains unknown about the underlying molecular mechanisms, especially those that act beyond the tumour microenvironment. Drosophila has a track record of high-impact discoveries about cell-autonomous growth regulation, and is well suited to now probe mysteries of tumour - host interactions.
View Article and Find Full Text PDFWe show that nematodes learn to associate food with a combination of proprioceptive cues and information on the structure of their surroundings (maze), perceived through mechanosensation. By using the custom-made Worm-Maze platform, we demonstrate that young adults can locate food in T-shaped mazes and, following that experience, learn to reach a specific maze arm. learning inside the maze is possible after a single training session, it resembles working memory, and it prevails over conflicting environmental cues.
View Article and Find Full Text PDFOld age is a period when people need physical, emotional, and psychological support. Depression is the most prevalent mental health problem among older adults and it contributes to increase in medical morbidity and mortality, reduces quality of life and elevates health care costs. Therefore early diagnosis and effective management are required to improve the quality of life of older adults suffering from depression.
View Article and Find Full Text PDFA seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma. The clinical presentation and management are being discussed.
View Article and Find Full Text PDFBackground: Economics and reimbursement have become a daily part of practicing physicians' lives. Yet, few internal medicine (IM) programs have offered formal curricula during residency about practice management or economics.
Objective: To determine perceived, desired, and actual knowledge of Medicare billing and reimbursement among residents compared with community-based General Internists.
Three cases of jellyfish envenomation which occurred in the Indian Ocean and the Andaman Sea are reported. In each instance the stinging occurred on the upper extremities, and impaired the circulation to the stung limb(s), with absent distal arterial pulses, regional cyanosis, and the threat of distal gangrene. One of the patients is seriously and permanently handicapped, with bilateral upper-limb numbness and paresis; another patient has permanent sensory loss; the third patient, who also had brachial-artery narrowing that was demonstrated by angiography, made an uneventful recovery.
View Article and Find Full Text PDFJ Indian Med Assoc
August 1986
Five hundred fifty-nine patients were evaluated for carotid artery disease in the Blood Flow Laboratory by the following direct and indirect noninvasive methods: 1. Periorbital doppler examination; 2. Ocular pneumoplethysmography (Gee); 3.
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