COVID-19 in children and the effect of schools reopening on potential transmission to household members.

Aim: The effect of reopening schools on children's contribution to SARS-CoV-2 transmission, especially within households, remains controversial. This study describes the clinical presentation of a large ambulatory COVID-19 paediatric cohort and evaluates the role of children in household transmission prior to and following school reopening.

Methods: A retrospective database cohort study was conducted in a large Health Maintenance Organization in Israel.

Conservative management of acute mastoiditis in children.

Objective: To review the current management of acute mastoiditis with critical emphasis on the role of myringotomy.

Design: A retrospective chart review.

Setting: Tertiary-care, university affiliated children's hospital.

C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast.

Recent studies demonstrate that members of the superfamily of G protein-coupled receptors (GPCRs) form oligomers both in vitro and in vivo. The mechanisms by which GPCRs oligomerize and the roles of accessory proteins in this process are not well understood. We used disulfide-trapping experiments to show that C5a receptors, expressed in mammalian cells, reside in membranes as oligomers (Klco, J.