Enhanced Yield and Gentle Purification of HIV for Cryo-Electron Tomography Analysis of Virion Maturation.

HIV is a lentivirus characterized by the formation of its mature core. Visualization and structural examination of HIV requires purification of virions to high concentrations. The yield and integrity of these virions are crucial for ensuring a uniform representation of all viral particles in subsequent analyses.

Strategically Designed Pd-Induced Changes in Alkaline Hydrogen Evolution Reaction and Oxygen Evolution Reaction Performances of Electrochemical Water Oxidation by the Galvanically Synthesized MoO/MoO Composite Thin Film.

Electrochemical water oxidation is believed to be an effective pathway to produce clean, carbon-free, and environmentally sustainable green energy. In this work, we report a simple, easy-to-construct, facile, low-cost, and single-step galvanic technique to synthesize a Pd-supported temperature-assisted MoO thin film nanocomposite for effective water oxidation. The most suitable nanocomposite exhibits very low overpotential at 10 mA/cm with smaller Tafel slope values for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) processes in an alkaline medium.

β-BiO-BiWO Nanocomposite Ornated with -Tetraphenylporphyrin: Interfacial Electrochemistry and Photoresponsive Detection of Nanomolar Hexavalent Cr.

Hexavalent chromium exposure via inhalation, ingestion, or both has been proven to adversely affect internal organs, induce toxic effects, cause allergies, and contribute to the development of cancer. It requires a substantial and challenging effort to detect several heavy metal ions conveniently, sensitively, and reliably by using materials that are easy to synthesize and have a high yield. The impact of light on the electrocatalytic oxidation/reduction process proves an environmentally friendly methodology with numerous applications in pollution control.

Strategic Synthesis of Heptacoordinated Fe Bifunctional Complexes for Efficient Water Electrolysis.

In this research, highly efficient heterogeneous bifunctional (BF) electrocatalysts (ECs) have been strategically designed by Fe coordination (C ) complexes, [Fe L (H O) Cl ] (C1) and [Fe L (H O) (SO )].2(CH O) (C2) where the high seven C number synergistically modifies the electronic environment of the Fe centre for facilitation of H O electrolysis. The electronic status of Fe and its adjacent atomic sites have been further modified by the replacement of -Cl in C1 by -SO in C2.

Correction: Highly active spherical amorphous MoS: facile synthesis and application in photocatalytic degradation of rose bengal dye and hydrogenation of nitroarenes.

[This corrects the article DOI: 10.1039/C5RA19442C.].

A Highly Sensitive Luminescent Upconversion Nanosensor for Turn-On Detection of As.

A luminescent nanoprobe (N), MnO-modified Er/Yb-codoped AgMoO upconversion nanoparticles (UCNPs; cod-AMO-3/MnO), was constructed for rapid, sensitive, and selective "turn-on" detection of trace As. Herein, two kinds of luminescent Ns were developed based on luminescence resonance energy transfer (LRET) between cod-AMO-3 as the energy donor and MnO as the energy acceptor. By using MnO as the matrix in cod-AMO-3/MnO fluorometric assay, the upconversion luminescence (UCL) intensity () of the cod-AMO-3 probe was quenched significantly through LRET, illustrating MnO as an efficient quencher for UCL.

Variability of ambient black carbon concentration in the Central Himalaya and its assessment over the Hindu Kush Himalayan region.

During 2015-2018, eight black carbon (BC) monitoring sites were established in Nepal and Bhutan to fill a significant data gap regarding BC measurement in Central Himalaya. This manuscript analyzes and presents data from these eight stations and one additional station on the Tibetan plateau (TP). Complex topography, varied emission sources, and atmospheric transport pathways significantly impacted the BC concentrations across these stations, with annual mean concentrations varying from 36 ng m to 45,737 ng m.

Tetraphenylporphyrin Decorated BiMoO Nanocomposite: Its Twin Affinity of Oxygen Reduction Reaction and Electrochemical Detection of 4-Nitrophenol.

A selective electrode for oxygen reduction reaction (ORR) and electrocatalytic reduction of 4-nitrophenol (-NP) was fabricated on a glassy carbon electrode using organic-inorganic BiMoO/HTPP nanocomposites with different weight percentages of tetraphenylporphyrin, synthesized by the solvothermal process. Materials thus synthesized were characterized through UV-Vis diffuse reflectance spectroscopy, X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDX), high-resolution transmission electron microscopy (HR-TEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) analysis. The electrocatalytic performance of the modified electrode toward ORR in the 0.

One pot solvent assisted syntheses of AgSbS nanocrystals and exploring their phase dependent electrochemical behavior toward oxygen reduction reaction and visible light induced methanol oxidation reaction.

A huge variety of silver based ternary sulfide semiconductors (SCs) have been considered for the sustainable advancement of renewable energy sources. Herein, we have synthesized two important classes of newly emerging semiconductor nanocrystals (NCs) Ag3SbS3 (SAS), i.e.

Numerical simulations of different sectoral contributions to post monsoon pollution over Delhi.

The National Capital Region (NCR) of India, Delhi, has experienced high post-monsoon pollution along with several peak pollution episodes in recent years. Diwali, the festival of lights, which is among the biggest festivals of India celebrated during the post-monsoon season, is also considered a pollution event associated as it is with the lighting of a large number of firecrackers. 2016 Diwali pollution episode continued for a week creating severe discomfort to residents of Delhi, prompting the judiciary to ban the sale and use of firecrackers in Delhi from 2017 onwards.

Encountering Chronic Sore Throat: How Challenging is it for the Otolaryngologists?

To explore and diagnose the underlying causes of chronic, recalcitrant sore throat. In this descriptive, cross-sectional study spanning 3 years (January 2014-December 2016), 1580 patients with chronic sore throat (>12 weeks duration, despite conventional medication) were evaluated for the possible cause(s) in a tertiary care teaching institute of eastern India, through proper history, appropriate investigations, and a self-designed algorithm. The common causes for chronic sore throat were chronic tonsillopharyngitis, gastroesophageal reflux disorder, submandibular sialadenitis, and laryngopharyngeal reflux disorder, respectively.

Advanced catalytic performance of amorphous MoS for degradation/reduction of organic pollutants in both individual and simultaneous fashion.

A cluster [(S)Mo(S)Mo(S)], has been used to synthesise molybdenum sulfide microparticles (MPs) by solvothermal treatments under inert environment. During synthesis, surfactants i.e.

Single source precursor driven phase selective synthesis of Au-CuGaS heteronanostructures: an observation of plasmon enhanced photocurrent efficiency.

The design of new functional metal-semiconductor heteronanostructures with improved photovoltaic efficiencies has drawn significant attention because of their unprecedented properties and potential applications. Herein, we report a phase selective synthesis of ternary CuGaS (wurtzite and tetragonal) by simple solution based thermal decomposition of a new binuclear single molecular precursor [Ga(acda)Cu(PPh)]NO (acda = 2-aminocyclopentene-1-dithiocarboxylic acid, PPh = triphenylphosphine) where the phase selectivity has been achieved easily by changing the combination of surface active agents. Furthermore, we have extended our approach to develop a well-controlled synthetic strategy for the preparation of a Au-CuGaS heteronanocomposite with both the phases.

Absence of KCNQ4 mutation in Bengali families with ADNSHL originated from West Bengal, India.

Objective: Autosomal Dominant Non-Syndromic Hearing Loss (ADNSHL) is extremely heterogeneous in nature. More than 60 loci with 30 different genes have been identified linked to ADNSHL. Mutation in KCNQ4 is considered as one of the most common causative factor responsible for ADNSHL.

Genetic Alterations in Pendrin (SLC26A4) Gene in Adult Hypothyroid Patients.

Current study was aimed to screen the gene in 127 nonautoimmune and noncongenital hypothyroid patients, who were under optimal iodine nutrition and devoid of any characteristics of Pendred syndrome from eastern part of Indian population. 8 single nucleotide variants/mutations were identified in heterozygous state in 20% patient population, which include 1 novel nonsynonymous (p.C18S), 1 novel intronic (g.

Efficient Charge Extraction from CdSe/ZnSe Dots-on-Plates Nanoheterostructures.

An efficient and a selective charge extraction from a new type of heterostructured material is demonstrated: the quasi-type-II structure formed upon deposition of ZnSe quantum dots on CdSe nanoplatelets, termed as CdSe/ZnSe dots-on-plates (DoPs) heterostructures. Insights into the charge extraction mechanism are gained from the present studies. Quenching experiments on nanoplatelets (NPLs) and DoPs using electron (benzoquinone) and hole (pyridine) quenchers show the possibility of electron extraction leaving behind the hole in the nanostructures.

Enhanced photocatalytic performance of morphologically tuned Bi2S3 NPs in the degradation of organic pollutants under visible light irradiation.

Here in, morphologically tuned Bi2S3 NPs were successfully synthesized from a single-source precursor complex [Bi(ACDA)3] [HACDA=2-aminocyclopentene-1-dithiocarboxylic acid] by decomposing in various solvents using a simple solvothermal method. The as-obtained products were characterized by XRD, TEM, UV-vis spectroscopy and BET surface area measurements. Structural analyses revealed that the as-prepared Bi2S3 NPs can be tuned to different morphologies by varying various solvents and surfactants.

Spectrum and frequency of GJB2, GJB6 and SLC26A4 gene mutations among nonsyndromic hearing loss patients in eastern part of India.

Genetically caused nonsyndromic hearing loss is highly heterogeneous. Inspite of this large heterogeneity, mutations in the genes GJB2, GJB6 and SLC26A4 are major contributors. The mutation spectrum of these genes varies among different ethnic groups.

Haemangioma of cheek different presentation and management.

Though haemangioma of cheek is not a very uncommon entity, here we are presenting a case series of four such cases of haemangioma cheek of completely different presentation. One of which is classical maxillary haemangioma and the rest of the others have different and unusual presentations. They all have different radiological features and were managed successfully by different surgical approaches without any recurrence.

Bis{[2,2'-(5,8,11-tri-thia-2,14-di-aza-penta-deca-1,14-diene-1,15-di-yl)diphenolato]palladium(II)} aceto-nitrile monosolvate.

The asymmetric unit of the title compound, [Pd(C22H26N2O2S3)]2·CH3CN, contains two complex mol-ecules and a single uncoordinated lattice aceto-nitrile solvent mol-ecule. The Pd(II) cations have a trans-N2O2 square-planar geometry and the superposition of the two crystallographically independent Pd(II) complexes yields an overall r.m.

A novel amperometric biosensor for hydrogen peroxide and glucose based on cuprous sulfide nanoplates.

A facile, greener and template free route has been developed to produce cuprous sulfide (CuS) nanoplates (NPs) with average diameters of 70-150 nm, via one step solvothermal decomposition of a single-source precursor (SSP) Cu(ACDC) [ACDC = 2-aminocyclopentene-1-dithiocarboxylate] in the presence of ethylenediamine (EN) and triethylenetetramine (TETA) as structure orienting agents. The precursor complex and nanomaterials were thoroughly characterized by several common techniques and measurements, which give the composition and characteristics of the materials. Amperometric biosensors for hydrogen peroxide (HO) and glucose have been constructed by immobilizing the synthesized CuS NPs in glutaraldehyde on a glassy carbon (GC) electrode using a direct drop-coating method.

Electrocatalytic activity of silver nanoparticles modified glassy carbon electrode as amperometric sensor for hydrogen peroxide.

A simple chemical route has been applied for the preparation of quasi-spherical silver (Ag) nanoparticles (NPs) with average diameter of 265 and 8 nm. The as prepared products were characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and UV-vis absorption spectroscopy. Ag NPs immobilized on glassy carbon (GC) electrode showed a superior electrocatalytic activity for the reduction of hydrogen peroxide (H2O2) in aqueous medium.

CuS nanoparticles as a mimic peroxidase for colorimetric estimation of human blood glucose level.

CuS nanoparticles (NPs) was synthesized through a simple and green method using water soluble precursor complex [CuL2(H2O)2]Cl2 (L=pyridine 2-carboxamide) and was characterized by X-ray diffraction analysis (XRD), transmission electron microscopy (TEM) and UV-Vis spectroscopic techniques. The as-prepared CuS NPs (covellite) was demonstrated to possess intrinsic peroxidase-like activity using 3,3',5,5'-tetramethylbenzidine (TMB), as a peroxidase substrate, in presence of H2O2 which show good affinity towards both TMB and H2O2. Using this TMB-H2O2 catalyzed color reaction; the CuS NPs was exploited as a new type of biosensor for detection and estimation of glucose through a simple, cheap and selective colorimetric method in a linear range from 2 to 1800 μM with a detection limit of 0.

Inhibition of TNF-α, and NF-κB and JNK pathways accounts for the prophylactic action of the natural phenolic, allylpyrocatechol against indomethacin gastropathy.

Background: The gastro-intestinal disorders, induced by the NSAIDs including indomethacin (IND) remain unresolved medical problems. Herein, we disclose allylpyrocatechol (APC) as a potential agent against IND-gastropathy and rationalize its action mechanistically.

Methods: Mice were pre-treated with APC for 1h followed by IND (18mgkg(-1)) administration, and the ulcer-prevention capacity of APC was evaluated on the 3rd day by histology.