Reviewing the Rare Association Between Progestogen-only Implant and Pulmonary Embolism in a Woman with Multiple Cardiovascular Risk Factors: A Case Report.

Pulmonary embolism (PE) is a recognized complication of hormonal contraceptive use, but the risk associated with progestogen-only implants in women with multiple cardiovascular (CV) risk factors remains uncertain. We present the case of a woman in her early forties with multiple CV risk factors, including obesity, obstructive sleep apnoea, and hypertension, who developed bilateral PE while using a progestogen-only implant. This case highlights the potential increased risk of PE in women with multiple CV risk factors using progestogen-only implants, warranting further investigation and cautious clinical decision-making.

Mixed connective tissue disease complicated by heart failure in Ile-Ife, Nigeria: management challenges in a resource-limited economy.

Background: Mixed connective tissue disease (MCTD; also known as Sharp's syndrome) is a rare autoimmune inflammatory disorder characterized by high titer of U1 ribonucleoprotein (U1RNP) antibody and clinical and serological overlap of systemic lupus erythematosus, systemic sclerosis, and polymyositis. The diagnosis is based on clinical and serological factors in criteria such as Alarcon-Segovia, Khan, Kusakawa, and Sharps. Cardiac disease can be a complication of connective tissue disease (CTD).