Publications by authors named "Adeyemi I Adeleye"
Article Synopsis
- Multidrug resistant bacterial pathogens are widespread and can evade antibiotics through various mechanisms, leading to significant public health issues related to infections such as urinary tract and gastrointestinal infections.
- This study examined 32 bacterial strains from clinical samples for their antibiotic resistance, biofilm formation, and efflux pump activity using standard testing methods and molecular techniques.
- The results showed all isolates were resistant to multiple commonly used antibiotics, with varying levels of resistance and biofilm formation, highlighting the need for increased monitoring and control measures for antibiotic resistance in healthcare settings.
Antimicrobial resistance genetic determinants and susceptibility profile of Pseudomonas aeruginosa isolated from clinical samples in a tertiary hospital in Ogun State, Nigeria.
Trans R Soc Trop Med Hyg
July 2024
Background: Genetic determinants are known to promote antibiotic resistance through horizontal gene transfer.
Methods: We molecularly characterized integrons, plasmid replicon types and metallo-β-lactamase-encoding genes of 38 Pseudomonas aeruginosa strains isolated from clinical samples.
Results: The P.
Multidrug resistance and invasiveness of non-typhoidal (NTS) serovars have in recent times brought to the fore the public health risk associated with salmonellosis. This study was aimed at profiling NTS serovars isolated from food animals and humans for their susceptibility to antibiotics and plasmid replicon types. Forty seven NTS serovars were profiled for their susceptibility to antibiotics using the disk diffusion method.
View Article and Find Full Text PDFBackground: Multidrug resistance efflux pumps and biofilm formation are mechanisms by which bacteria can evade the actions of many antimicrobials. Antibiotic resistant non-typhoidal serovars have become wide spread causing infections that result in high morbidity and mortality globally. The aim of this study was to evaluate the efflux pump activity and biofilm forming capability of multidrug resistant non-typhoidal (NTS) serovars isolated from food handlers and animals (cattle, chicken and sheep) in Lagos.
View Article and Find Full Text PDFEvaluation of efflux pump activity and biofilm formation in multidrug resistant clinical isolates of Pseudomonas aeruginosa isolated from a Federal Medical Center in Nigeria.
Ann Clin Microbiol Antimicrob
February 2021
Background: Pseudomonas aeruginosa an opportunistic pathogen, is widely associated with nosocomial infections and exhibits resistance to multiple classes of antibiotics. The aim of this study was to determine the antibiotic resistance profile, biofilm formation and efflux pump activity of Pseudomonas strains isolated from clinical samples in Abeokuta Ogun state Nigeria.
Methods: Fifty suspected Pseudomonas isolates were characterized by standard biochemical tests and PCR using Pseudomonas species -specific primers.
Objective: Nosocomial and community acquired multidrug resistant Klebsiella infections are wide spread resulting in high morbidity and mortality due to limited number of antibiotics treatment options. This study investigated efflux pump activity, biofilm forming potential and antibiotic susceptibility profile of Klebsiella spp. isolated from clinical samples in a tertiary hospital in Lagos Nigeria.
View Article and Find Full Text PDFOutbreaks of remain a major public health problem globally. This study determined the diversity and antibiotic resistance gene profile of serovars isolated from humans and food animals. Using standard methods, spp.
View Article and Find Full Text PDFObjectives: The aim of this study was to determine the occurrence of 16S rRNA mutations associated with low-level tetracycline resistance in Helicobacter pylori isolates from adult dyspeptic patients in South West Nigeria.
Methods: Susceptibility testing to tetracycline of 50 H. pylori isolates was performed by Etest.