Publications by authors named "Adewunmi C"

Purpose: Clinical trials are essential to the advancement of cancer care. However, clinical trial knowledge and participation remain critically low among adult patients with cancer. Health information technology (HIT) could play an important role in improving clinical trial knowledge and engagement among cancer survivors.

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Objective: Social media is becoming recognized as an effective platform for cancer health promotion, education, care, and support. However, its utility as a health promotion tool remains relatively unexplored.

Methods: Using cross-sectional data from the 2017-2020 Health Information National Trends Survey, we evaluated health-related usage of social media among cancer survivors and individuals without a history of cancer.

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Background: Over the past year, studies have shown potential in the applicability of ChatGPT in various medical specialties including cardiology and oncology. However, the application of ChatGPT and other online chat-based AI models to patient education and patient-physician communication on colorectal cancer screening has not been critically evaluated which is what we aimed to do in this study.

Methods: We posed 15 questions on important colorectal cancer screening concepts and 5 common questions asked by patients to the 3 most commonly used freely available artificial intelligence (AI) models.

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Purpose: The incidence of anal cancer is on the rise in the US, especially among high-risk groups. This study examined the prevalence and determinants of awareness of the causal relationship between HPV and anal cancer among US adults.

Methods: Study data was obtained from the 2017 to 2020 iterations of the Health Information National Trends Survey.

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Article Synopsis
  • The incidence of colorectal cancer (CRC) in young adults under 50 has been increasing, prompting the American Cancer Society to lower the recommended screening age to 45 in 2018.
  • A study analyzed data from over 7,500 adults aged 45-75 to identify the sociodemographic factors that influence CRC screening rates; results showed overall screening rate at 76%.
  • Key predictors of screening included increasing age, being Black, having higher education, health insurance, access to a primary care provider, and having a comorbidity; however, current smokers and Hispanic adults aged 50-64 were less likely to be screened, raising concerns about their risk.*
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Article Synopsis
  • Colorectal cancer (CRC) is a major health issue in the U.S., particularly affecting smokers, and health information technology (HIT) could help improve screening rates.
  • Analysis of data from over 7,400 adults showed that more than 20% of current smokers lacked access to HIT tools, and those with access tended to use them less than never smokers.
  • Among former smokers, utilizing HIT for tasks like checking test results and making health appointments was linked to higher CRC screening participation, highlighting a challenge for current smokers with limited HIT access.
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We report a case of localized sarcomesothelioma detected during screening via a low-dose CT (LDCT) scan. The patient is a 71-year-old female, a current 56-pack-year cigarette smoker with a past medical history of myocardial infarction and stroke with a Zubrod score of zero. A screening LDCT revealed a 1.

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Autoimmune hemolytic anemia (AIHA) is a rare disease characterized by autoantibodies directed at red blood cells. Patients typically present with anemia and are diagnosed by positive direct antiglobulin (DAT) test. AIHA is subclassified into warm or cold based on antibodies involved and depending on their optimal temperature in which they react with RBC antigens.

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Ethnopharmacological Relevance: Locally, among the Yoruba speaking people of South Western, Nigeria, the bulb of Crinum jagus (CJ), known as "ogede odo" is used to treat malaria and as an anthelmintic among other uses.

Aims Of This Study: Study aimed at identifying the purified active fractions and constituents of this fraction in an antiplasmodial activity-guided process.

Materials And Methods: Antiplasmodial activity-guided fractionation of the bulb and leaf extracts of CJ was investigated against chloroquine-sensitive (NK 65) Plasmodium berghei using 4-day suppressive and prophylactic methods.

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BACKGROUND Pleural effusions are frequently seen among patients with hematopoietic stem cell transplantation (HSCT). In the majority of cases, they are related to infections and volume overload. Medications have also been reported to cause pleural effusion in the general population, albeit very rarely.

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This study explored the influence of athletic identity and sports participation on the psychological well-being of athletes during a pandemic. The objective of the study was to understand the psychological impact of the coronavirus lockdown measure on athletes who were not able to carry out their normal daily routine. Athletes from nine different sports completed an online survey during the sixth week of the total lockdown in Nigeria.

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The extracts of nine selected Nigerian medicinal plants were investigated on Trypanosoma brucei brucei infected mice. The anti-inflammatory properties of hexane fraction of the most promising U. chamae extract was assessed by acute oedema of the mice paw model while the modulatory effect of the extract on Delayed-Type Hypersensitivity (DTH) response on in vivo leucocytes mobilization was evaluated.

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Eugenia uniflora, used ethnomedically in some tropical countries as an anti-infective, has shown anti-malarial and anti-trypanocidal activities. Therefore using bioactivity guided fractionation, anti-trichomonal activity of E. uniflora leaf was investigated.

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The antioxidant principles isolated from the various parts of the plant are verminoside (leaf, stem bark and flowers; EC(50) = 2.04 µg/ml), Specioside (flowers; EC(50) = 17.44 µg/ml), Kampeferol diglucoside (leaf; EC(50) = 8.

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In malarial endemic countries especially in the tropics, conventional antimalarial drugs are used with herbal remedies either concurrently or successively. Khaya grandifoliola is one of such popular herbs used in the treatment of malaria.Various doses of ethanol extract of K.

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Article Synopsis
  • Clausena lansium, also known as Fool's Curry Leaf, is traditionally used for treating conditions like bronchitis, malaria, and gastrointestinal inflammation, and serves as a substitute for the Curry leaf tree.
  • The study assessed the medicinal properties of the plant's stem bark, focusing on its effects against inflammation, liver toxicity, diabetes, and a specific parasite (Trichomonas gallinae).
  • Results indicated that the dichloromethane extract was more effective against Trichomonas, and the methanolic extract significantly improved insulin levels, demonstrating potential anti-diabetic properties primarily through stimulating insulin release.
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Aim Of The Study: The ethanolic stem bark extract of Harungana madagascariensis (Hypericaceae), (Choisy) Poir were evaluated for their activities on Trichomonas gallinae (Rivolta) Stabler isolated from the pigeon (Columba livia). It was also tested for their anti-malarial activity on N67 Plasmodium yoelii nigeriensis (in vivo) in mice and on Plasmodium falciparum isolates in vitro.

Materials And Methods: The anti-trichomonal screening was performed in vitro using Trichomonas gallinae culture.

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The methanolic extract of Murraya koenigii leaf was screened for toxicological and biochemical effects on rats because of the folkloric uses as an anti-dysentery and anti-diabetes. The extract was moderately toxic (LD(50)=316.23 mg/kg body weight) to rats and had appreciable effect on the liver and kidney at higher doses leading to liver inflammation.

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Antioxidant and cytoprotective activities of boiled, cold, and methanolic extracts of nine edible vegetables in Southwest Nigeria were evaluated in the 1,1-diphenyl-2-picrylhydrazyl free radical assay and hemagglutination assay in bovine erythrocytes, respectively. Crassocephalum rubens showed the highest antioxidant activity (56.5%), Solanum americanum and Vernonia amygdalina exhibited moderate antioxidant activity (26.

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Dorstenia barteri and D. convexa extracts and some isolated components of the former were investigated for effectiveness against Trichomonas gallinarum and compared with quercetin and quercitrin. The antioxidant activity of the extracts/compounds was also determined.

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The prevalence of S. haematobium infection in 18 Local Government Area (LGA) in Ondo state was determined by examining pupils from randomly selected schools in the state. A total of 4266 urine samples were examined and 1303 (30.

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The fruit of Tetrapleura tetraptera (Taub) [Fabaceae] is frequently used in Tropical African traditional medicine for the management and/or control of an array of human ailments, including arthritis and other inflammatory conditions, asthma, diabetes mellitus, hypertension, epilepsy, schistosomiasis, and so on. The present study was undertaken to examine the anti-inflammatory and hypoglycaemic effects of Tetrapleura tetraptera (Taub) fruit aqueous extract in rats. Fresh egg albumin-induced pedal oedema and streptozotocin (STZ)-induced diabetes mellitus were used as experimental test models of inflammation and diabetes.

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The present study was undertaken to investigate the antinociceptive and anti-inflammatory activities of the leaf and twig extracts of Dorstenia barteri (Moraceae) in mice. Both the leaf and twig extracts of Dorstenia barteri at 50, 100 and 200 mg/kg showed significant (P < 0.05-0.

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