Publications by authors named "Adetola O Daramola"
Article Synopsis
- This study focuses on the classification of glioma cases at Lagos University Teaching Hospital, utilizing the 2021 WHO brain tumor classification that combines histomorphology and molecular features, despite limited resources.
- Of the 56 brain tumor cases examined, 52 were assessed, revealing that 35% of the initial diagnoses changed after applying the WHO criteria, with some diagnoses being upgraded and others downgraded.
- The results emphasize the importance of molecular testing in improving brain tumor diagnoses in resource-limited settings like Nigeria and highlight the challenges faced in global health disparities in neuro-oncology.
Introduction: Androgen receptor (AR) is one of the predominant nuclear hormone receptors in invasive breast cancer and can be explored as a biomarker of response for targeted anti-androgen therapy, especially in the setting of triple negative breast cancer (TNBC). Luminal AR is a distinct subtype amongst TNBC cases following gene expression studies. TNBC is higher in Africans (23%-82%) and African-Americans (29.
View Article and Find Full Text PDFBackground: Although fine needle aspiration cytology (FNAC) is highly accurate for detecting breast malignancies, concerns remain among cytopathologists about false-positive and false-negative diagnoses. Cell block (CB) preparations have been advocated by some cytopathologists as one of the methods to improve and consolidate the diagnostic accuracy of FNAC. The aim of this study was to determine the diagnostic utility of CB in FNAC of palpable breast lesions among female patients.
View Article and Find Full Text PDFVitamin K is present in the testes though its actual function in male reproduction is poorly understood. This study investigated the harmful effect of extrahepatic vitamin K insufficiency on the testicular structure. Sprague-Dawley rats were fed with a diet containing warfarin for 2, 4 and 8 weeks; control animals received a standard diet without warfarin.
View Article and Find Full Text PDFContext: -Web-based learning is a major component of distance education.
Objective: -To explore Web-based applications for pathology teaching in resource-limited sub-Saharan Africa.
Design: -The participants were consultant pathologists and trainees drawn from tertiary institutions in Nigeria.
Small airways diseases are not uncommon in childhood. They account for about 28.4% of hospital admissions for lower respiratory tract infections in South West Nigeria, most of which are due to respiratory syncytial virus (RSV) infection.
View Article and Find Full Text PDFPurpose: To assess the completeness and accuracy of breast cancer pathologic reporting in Nigeria.
Materials And Methods: The histologic parameters provided in breast cancer pathology reports at a large teaching hospital in Nigeria were assessed. The corresponding slides were reviewed after the United Kingdom Royal College of Pathologists guidelines, and results were compared.
Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution.
Int J Breast Cancer
December 2015
Background. Management of breast lumps can be challenging in resource poor settings. Fine-needle aspiration cytology (FNAC) especially when used with cell block can help improve affordability for the patients.
View Article and Find Full Text PDFBackground: Croton penduliforus (Euphorbiaceae) is a tropical evergreen plant widely distributed in Africa. Its seeds are used in folklore medicine as laxative, as well as a major component of herbal contraceptive and antifibroid decoction.
Objective: This study is to investigate the oral acute toxicity and histological effects of Croton penduliflorus seed oil in mice.