Publications by authors named "Adesola Ogunleye"

Article Synopsis
  • Monkeypox (MPX) is a rare viral disease similar to smallpox, with sporadic outbreaks in Nigeria since 2017, worsened by the COVID-19 pandemic impacting disease monitoring.
  • This study aimed to enhance the surveillance of MPX in three priority states (Rivers, Delta, and Bayelsa) by training community volunteers to actively search for cases over a three-month period.
  • The enhanced surveillance led to the identification of 25 suspected MPX cases, with 3 confirmed positives, demonstrating that better monitoring can significantly improve reporting and response to the disease in affected areas.
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Smallpox eradication, coordinated by the WHO and certified 40 years ago, led to the cessation of routine smallpox vaccination in most countries. It is estimated that over 70% of the world's population is no longer protected against smallpox, and through cross-immunity, to closely related orthopox viruses such as monkeypox. Monkeypox is now a re-emerging disease.

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Background: The cholera outbreak in 2018 in Nigeria reaffirms its public health threat to the country. Evidence on the current epidemiology of cholera required for the design and implementation of appropriate interventions towards attaining the global roadmap strategic goals for cholera elimination however seems lacking. Thus, this study aimed at addressing this gap by describing the epidemiology of the 2018 cholera outbreak in Nigeria.

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Background: In September 2017, Nigeria experienced a large outbreak of human monkeypox (HMPX). In this study, we report the outbreak experience and response in the Niger Delta University Teaching Hospital (NDUTH), Bayelsa state, where the index case and majority of suspected cases were reported.

Methods: In a cross-sectional study between September 25th and 31st December 2017, we reviewed the clinical and laboratory characteristics of all suspected and confirmed cases of HMPX seen at the NDUTH and appraised the plans, activities and challenges of the hospital in response to the outbreak based on documented observations of the hospital's infection control committee (IPC).

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Article Synopsis
  • * From December 2016 to June 2017, there were 14,518 suspected cases, with laboratory tests confirming 433 positive cases, primarily caused by Neisseria meningitidis serogroup C.
  • * In response to the outbreak, approximately 2.1 million individuals aged 2-29 were vaccinated, and the outbreak was declared over on June 15, 2017, highlighting the importance of ongoing surveillance and lab testing for future outbreaks.
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