Publications by authors named "Adesegun S"

Ethnopharmacological Relevance: Coccinia barteri (Hook. F.) is traditional used in Southeast of Nigeria in management of fever.

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Background: Petersianthus macrocarpus (Lecythidaceae) is widely used in the folk medicine in Nigeria to relieve pain and fever associated with malaria. This study evaluated the analgesic and antioxidant activities of the methanol extract and fractions of the stem bark of the plant.

Materials And Methods: The analgesic activity was determined in mice using hotplate and acetic acid-induced writhing models.

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From the ethanol extract of the stem of Planch, two known compounds and were isolated and identified as triterpenoid saponins 3-O-[α-L-arabinofuranosyl- (1→3)-α-L-rhamnopyranosyl- (1→2)-α-L-arabinopyranosyl-]-hederagenin and 3-O- [α-L-arabinopyranosyl- (1→3)-α-L-rhamnopyranosyl (1→2)-α-L-arabinopyranosyl-]-hederagenin. The structures were established by physicochemical and spectroscopic investigations (MS and NMR) as well as comparison of literature data. The compound exhibited anticancer activity against human colon carcinoma H-116, human lung carcinoma A-549 and human lung carcinoma HT-29 cell lines with IC 5.

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A methanol extract of dried leaves of Melanthera scandens was examined for antioxidant activities using a variety of assays, including 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power, ferrous chelating, and ferric thiocyanate methods with ascorbic acid and EDTA as positive controls. The extract showed noticeable activities in most of these in vitro tests. The amount of phenolic compounds in the extract expressed in gallic acid equivalent was found to be 52.

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The antioxidant activities of crude extract of Phaulopsis fascisepala leaf were evaluated and compared with alpha-tocopherol and BHT as synthetic antioxidants and ascorbic acid as natural-based antioxidant. In vitro, we studied its antioxidative activities, radical-scavenging effects, Fe(2+)-chelating ability and reducing power. The total phenolic content was determined and expressed in gallic acid equivalent.

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The stem bark extract of S. ellipticum (Hochst) Pax was investigated for its antioxidant properties in this study. The extract was evaluated for antioxidant activity in vitro in terms of its ability to inhibit lipid peroxidation and its free radical scavenging, reducing and metal chelation powers.

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Background And Objective: Many treatment options, including non-pharmacological and pharmacological measures, have been recommended in the management of osteoarthritis (OA). Among the non-pharmacological approach is physiotherapy, which involves the use of physical modalities like, heat therapy, exercise therapy, electrical stimulation, therapeutic ultrasound, iontophoresis, and phonophoresis. This study was therefore designed to compare the effectiveness of 0.

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