Non-intuitive Behavior of Polymer-Ciprofloxacin Nanoconjugate Suspensions: a Tool for Flexible Oral Drug Delivery.

Ciprofloxacin (CPX) is prone to spontaneous self-aggregation and formation of supramolecular dimers (π - π stacking) due to its complicated surface chemistry which has been associated with its anomalous solubility and instability in aqueous systems particularly near neutral pH. The surface characteristic of ciprofloxacin was modified through non-intuitive counterion interaction between CPX and diethylaminoethyl dextran (DDEX) to form nanoconjugate assembly. The CPX-DDEX nanoconjugate was confirmed by FTIR, SEM, DSC, TGA, and H-NMR.

What is in Nigerian waters? Target and non-target screening analysis for organic chemicals.

Emerging organic contaminants (e.g., active pharmaceutical ingredients and personal care products ingredients) are ubiquitous in the environment and potentially harmful to ecosystems, have gained increasing public attention worldwide.

Chitosan-induced Synergy for Extended Antimicrobial Potency and Enhanced In Vitro Drug Release of Free Base Ciprofloxacin Nanoplexes.

Background: Ciprofloxacin free base is practically insoluble in aqueous medium (0.0011 and 0.09 mg/mL at 25 and 37°C respectively).

Preliminary Anti-Fungal Activity of the Aqueous Bark Extract of Calotropis procera (ASCLEPIADACEAE).

Background: Calotropis procera is a species of flowering plant which belongs to the Asclepiadaceous family. Its other names are Apple of Sodom, Giant Milkweed and Swallow-wort. It's native to Africa and Asian countries where they exist as a spreading shrub or small tree with height of about 4m.