Effects of Lipid Headgroups on the Mechanical Properties and In Vitro Cellular Internalization of Liposomes.

We performed all-atom and coarse-grained simulations of lipid bilayer mixtures of the unsaturated lipid DOPC, with saturated lipids having the same 18-carbon acyl tails and different headgroups, to understand their mechanical properties. The secondary lipids were DSPG, DSPA, DSPS, DSPC, and DSPE. The DOPC:DSPG system with 65:35 molar ratio was the softest, with area compressibility modulus ∼ 22% smaller than the pure DOPC value.

Prevalence of Mental Ill-Health among Visually Impaired Patients in a Tertiary Institution in Southwestern Nigeria.

Background: To study the mental health status of patients with visual impairment in a tertiary institution in Southwestern Nigeria.

Objectives: To determine the mental health status of individuals with loss of vision in Ogbomoso and associated factors.

Methodology: A descriptive cross-sectional study.

Mineralogy and geochemistry of the sandstone facies of Campanian Lokoja formation in the Southern Bida basin, Nigeria: implications for provenance and weathering history.

The upper Cretaceous Lokoja Formation is the earliest deposited stratigraphic unit in the intracratonic Bida Basin, Nigeria. It consists predominantly of sandstone and offers a potential hydrocarbon reservoir in the basin. In this study, we investigated the bulk elemental (major, trace and rare earth elements) and mineralogical compositions of the sandstones for the determination of their compositional maturity, tectonic setting, source and weathering history.

Outdoor smoking in Nigeria: prevalence, correlates and predictors.

Background: There is a lack of data on smoking in outdoor-open bars in Nigeria that may translate into effective legislation on public smoking.

Method: This study determined the prevalence, demographic and clinical correlates as well as predictors of smoking among a community sample of 1119 patrons of open place bars in Ibadan, Nigeria. Data on current smoking was obtained using the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), while smoking intensity was calculated using the Pack-Year.

Prevalence of alcohol consumption and alcohol use disorders among outdoor drinkers in public open places in Nigeria.

Background: There is a rapid shift in the social context of drinking, with a large proportion of regular drinkers favouring outdoor-open space drinking, such as motor-parks, by the road sides, the majority of which are unlicensed premises for drinking.

Method: This study determined the prevalence and determinants of harmful or hazardous alcohol use and possible dependence, defined as a "likely alcohol use disorder" (AUD) in a community sample of 1119 patrons of open space drinking places in Ibadan, Nigeria, using the AUDIT. Scores of 8 and above signified a likely AUD.

Psychiatric Morbidity in Children with HIV/AIDS at a Tertiary Health Institution in North-central Nigeria.

Introduction: Children with human immunodeficiency virus (HIV) infection are living longer with the infection and are at risk of different complications. We assessed for the prevalence of and associated factors for psychiatric morbidity among HIV-infected children in a tertiary facility in Ilorin, Nigeria.

Methods: A descriptive cross-sectional, two-staged study involving 196 HIV-positive children (6-17 years).

Tear Film Functions and Intraocular Pressure Changes in Pregnancy.

Pregnancy related ocular changes are diverse with varied clinical outcome. In a cross-sectional, descriptive case control study, we evaluated tear film functions and intraocular pressure during pregnancy and compared the results with non-pregnant women. A total of 270 participants including 165 healthy pregnant women and 105 non-pregnant who were free from systemic and pre-pregnancy eye diseases were investigated.