Publications by authors named "Adepeju E Onasanya"
Background: Equid gammaherpesvirus 5 (EHV5) is closely related to equid gammaherpesvirus 2 (EHV2). Detection of EHV5 is frequent in horse populations worldwide, but it is often without a clear and significant clinical impact. Infection in horses can often present as subclinical disease; however, it has been associated with respiratory disease, including equine multinodular pulmonary fibrosis (EMPF).
View Article and Find Full Text PDFArticle Synopsis
- Equid gammaherpesvirus 2 (EHV2) is a virus found in horses that can cause respiratory disease in foals and has a diverse genetic makeup, with varying strains commonly co-existing in infected horses.
- Whole genome sequencing of 20 EHV2 isolates revealed significant differences in genome size, nucleotide sequence identity, and evidence of genetic recombination among the strains.
- The study suggests that the genetic diversity and evolutionary changes in EHV2 are largely influenced by recombination, highlighting its importance in the virus's adaptation and pathogenicity.
Infectious laryngotracheitis (ILT) is an upper respiratory tract disease of chickens that is caused by infectious laryngotracheitis virus (ILTV), an alphaherpesvirus. This disease causes significant economic loses in poultry industries worldwide. Despite widespread use of commercial live attenuated vaccines, many poultry industries continue to experience outbreaks of disease caused by ILTV.
View Article and Find Full Text PDFEndothelin-2 (EDN2), expressed at a narrow window during the periovulatory period, critically affects ovulation and corpus luteum (CL) formation. LH (acting mainly via cAMP) and hypoxia are implicated in CL formation; therefore, we aimed to elucidate how these signals regulate using human primary (hGLCs) and immortalized (SVOG) granulosa-lutein cells. The hypoxiamiR, microRNA-210 (miR-210) was identified as a new essential player in expression.
View Article and Find Full Text PDF