Anterior and Posterior Ocular Changes in Patients with Active and Inactive Ankylosing Spondylitis.

BACKGROUND The 6-item Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is a method for evaluating disease activity in ankylosing spondylitis (AS). This study included 78 patients with active and inactive AS and aimed to evaluate anterior and posterior segment ocular changes. MATERIAL AND METHODS Seventy-eight patients and 70 control subjects were enrolled in this study.

Assessment of the optic nerve, macular, and retinal vascular effects of COVID-19.

Objective: To evaluate the effects of SARS-CoV-2 infection on the optic nerve, macula, and retinal vascular structures.

Methods: This study included 129 participants recovering from COVID-19 and 130 healthy control subjects aged 18 to 55 years. The study was designed as observational and cross-sectional and was conducted between June 2020 and February 2021.

Changes in optical coherence tomography angiography in patients with vitamin D deficiency.

Purpose: 25-hydroxyvitamin D 25(OH)D] sufficiency has critical biological importance for the human body. Although there are several studies on the association between serum 25(OH)D levels and macular structure, the data in this regard are limited. This study mainly aimed to investigate macular microvascular structure using optical coherence tomography angiography (OCTA) in 25(OH)D deficiency.

Frequency of retinopathy of prematurity (ROP) in infants screened for ROP: two years follow-up results of a single center in Turkey.

Aim: The aim of this retrospective study was to determine the incidence of retinopathy of prematurity (ROP) in infants referred to our clinic for screening ROP.

Material And Method: The data of 729 infants who were referred to the ROP outpatient clinic of the Ophthalmology Unit of Erzincan Binali Yildirim University, Turkey between April 2018 and March 2020 were analyzed retrospectively. The gestational age and weight of the infants, stay in the neonatal intensive care unit, duration of oxygen therapy, and detailed ophthalmologic examination findings were recorded in the study.

Comparison of Six Methods of Central Corneal Thickness Measurement in Healthy Eyes.

Objectives: Several methods of measuring central corneal thickness (CCT) have been compared, however, the data are still limited and conflicting. The aim of this study was to determine the agreement of CCT measurements performed in healthy eyes using ultrasound pachymetry (USP), non-contact tono/pachymetry, specular microscopy, biometry, Scheimpflug-based corneal topography, and optical coherence tomography (OCT).

Methods: All of the participants underwent a complete ophthalmological examination.

An investigation on well-to-wheel emissions of passenger cars in Turkey.

Passenger cars are responsible for a great amount of energy consumption and emissions in the world. Turkey is one of the world's twenty largest emission producers. The reason behind this study is to determine the most appropriate energy source for passenger cars particularly in Turkey in terms of main vehicle emissions.

Retinal Microvascular Vessel Density Differences between Adult Athletes and Nonathletes.

Significance: Regular physical activity may affect the neurovascular structures. Many studies have shown the positive effects of physical activity on ocular disorders such as glaucoma, retinopathy, and macular degeneration. Athletes were expected to have a better retinal vascular structure compared with the nonathletes.

Protection against experimental cisplatin-induced optic nerve toxicity using resveratrol: A rat model study.

Aim: To investigate the effects of resveratrol on oxidative stress and inflammation parameters and histological alterations in cisplatin-induced optic nerve damage in a mouse model.

Material And Method: Thirty-six albino Wistar male rats were divided into three groups as control, 5 mg/kg cisplatin-administered (Cis) and 5 mg/kg cisplatin + 25 mg/kg resveratrol-administered (Cis + Res) animals. At the end of the experimental period, the rats were sacrificed with high-dose (50 mg/kg) thiopental sodium, and their optic nerves were dissected.

Logistic Regression Model Using Scheimpflug-Placido Cornea Topographer Parameters to Diagnose Keratoconus.

Purpose: Diagnose keratoconus by establishing an effective logistic regression model from the data obtained with a Scheimpflug-Placido cornea topographer.

Methods: Topographical parameters of 125 eyes of 70 patients diagnosed with keratoconus by clinical or topographical findings were compared with 120 eyes of 63 patients who were defined as keratorefractive surgery candidates. The receiver operating character (ROC) curve analysis was performed to determine the diagnostic ability of the topographic parameters.

Influences of Hypomagnesemia on Optic Nerve and Retinal Vascular Structure Determined Using Optical Coherence Tomography (OCT) Angiography.

: To evaluate the effects of low blood magnesium levels on the optic nerve, retina, and retinal vascular structure.: This observational and cross-sectional study was conducted between June 2019 and May 2020 with participants aged 20-39 years, who had a visual acuity of ≥20/20, the axial length of 22-24.5 mm, refractive defect spherical equivalent of ≤±3D, and intraocular pressure of ≤21 mm Hg.

Evaluation of the Optic Disc and Macula in Healthy Children Using Optical Coherence Tomography Angiography.

Objectives: To perform the measurements of the optic disc and macula in healthy children using optical coherence tomography angiography (OCTA) in order to determine the normative data values and compare these by age, gender, spherical equivalent (SE), and axial length (AL).

Materials And Methods: A total of 146 eyes belonging to 146 healthy children (74 girls, 72 boys) aged 6 to 16 years were included in this prospective study. Refraction and biometry measurements were performed.

WHAT IS THE INCIDENCE OF RETINOPATHY OF PREMATURITY (ROP) IN 'BIG' BABIES?: RESULTS OF A RETROSPECTIVE MULTICENTER STUDY.

Aim: This study aims to determine the incidence of ROP and to investigate its prognosis among premature babies with a BW of ≥2000 g.

Material And Method: We retrospectively analyzed the data of 1004 babies with BW≥2000 g admitted to the ROP Diagnosis and Treatment Centers of X University Hospital and X Hospital between 2018 and 2019. Examination findings were recorded according to the Classification of Retinopathy of Prematurity guideline.

The findings of corneal specular microscopy in patients with type-2 diabetes mellitus.

Background: We aimed to compare the morphological characteristics of corneal endothelial cells in type 2 diabetic patients and age-matched healthy subjects by specular microscopy. We also aimed to determine the association of corneal morphological features with the general characteristics and laboratory data of diabetic patients, including disease duration, haemoglobin A1c (HbA1c) levels and urine albumin creatinine ratio.

Methods: A total of 195 diabetic patients and 100 healthy controls were enrolled in the study.

Alterations in optical coherence tomography angiography findings in patients with high myopia.

Purpose: The aim of this study was to determine the macular changes using optical coherence tomography (OCT) and OCT-angiography (OCT-A) in eyes with high myopia. Determining the alterations in vascular structures can provide a clearer understanding of the pathophysiological mechanisms of this disease and help define new treatment options and preventive measures.

Materials And Methods: Ninety-two patients with high myopia (axial length ≥ 26 mm) and 70 control cases without any known systemic or ocular diseases were enrolled in this prospective study.

Ophthalmologic Manifestations and Retinal Findings in Children with Down Syndrome.

Purpose: To evaluate ocular findings in children with Down syndrome and to compare with the healthy children group.

Methods: The study patients were divided into two groups as the diagnosed Down syndrome group and the control group. The study was designed as a prospective and single-center study in Istanbul University Faculty of Medicine Department of Ophthalmology.

Normative Data Assessment of Vessel Density and Foveal Avascular Zone Metrics Using AngioScan Software.

: To establish a normative database for macular and peripapillary vessel densities (VD) and foveal avascular zone (FAZ) metrics in healthy subjects with the new version of AngioScan software of RS-3000 Advance (Nidek Co, Ltd) optical coherence tomography angiography (OCT-A) device.: The study design was prospective and cross-sectional. VDs of the SCP, deep capillary plexus (DCP), retinal peripapillary capillary plexus (RPCP) and FAZ area, perimeter and circularity index (CI) along with the structural OCT measurements were scanned by using the Nidek's RS-3000 Advance OCT-A device in healthy subjects.

Evaluation of Maculopathy in Patients Using Hydroxychloroquine.

Objectives: To determine length of hydroxychloroquine use and cumulative dose and evaluate the ocular effects by 10-2 central visual field test, microperimetry (MP), color fundus photography, optical coherence tomography (OCT), and fundus autofluorescence (FAF) in hydroxychloroquine users.

Materials And Methods: Patients who used hydroxychloroquine continuously for at least 2 years for various connective tissue diseases were included in the study. A total of 300 eyes of 150 patients aged 19-78 years who were followed due to risk of developing hydroxychloroquine maculopathy in the İstanbul University İstanbul Faculty of Medicine Ophthalmology Department between the years 1995-2017 were evaluated.