Publications by authors named "Adem Karaman"

Magnetic nanoparticles (MNPs) are produced for both diagnosis and treatment due to their simultaneous availability in magnetic resonance imaging (MRI) and magnetic hyperthermia (MHT). Extensive investigations focus on developing MNPs for individual MHT or MRI applications, but the development of MNPs for theragnostic applications has received very little attention. In this study, through efficient examination of synthesis conditions such as metal precursors, reaction parameters, and solvent choices, we aimed to optimize MNP production for effective utilization for MHT and MRI simultaneously.

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Pulmonary mucous gland adenomas (MGAs) originating in mucous-secreting cells in the bronchi are extremely rare benign tumours. Pulmonary chondroid hamartomas (PCHs) are the most common benign neoplasms of mesenchymal origin of the lung. This study reports an unusual case where MGA and PCH coexisted in a peripheral intra-parenchymal location.

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Article Synopsis
  • Gadolinium deposition in rat kidneys was studied following single and multiple doses, aiming to see how long it lasts and if there's a link between deposition levels and T1-weighted image intensity.
  • The study involved 70 rats divided into groups receiving varying doses, with assessments made at different time points using imaging and mass spectrometry.
  • Results showed more injections led to higher gadolinium levels, but there was little difference between low and medium doses, and T1 intensity measurement was found to be unreliable for gauging deposition.
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Alveolar echinococcosis is a life-threatening zoonotic disease caused by Echinococcus multilocularis. The disease usually primarily involves the liver and shows tumor-like growth. Early diagnosis of alveolar echinococcosis is difficult because the disease is usually asymptomatic in the early stages.

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Objective: This study aimed to determine the role of magnetic resonance imaging in minimizing radiation exposure, especially in the follow-up of pulmonary nodules.

Methods: Patients who applied to our hospital between April 2013 and August 2018 for various reasons and had lung-mediastinal dynamic magnetic resonance imaging and thoracic computed tomography were included in the study. A total of 194 patients were included in the study, involving 84 females and 110 males.

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Determining the behavior of aerosol drug particles is of vital importance in the treatment of respiratory tract diseases. Despite the development of imaging techniques in the pulmonary region in recent years, current imaging techniques are insufficient to detect particle deposition. Computational fluid dynamics (CFD) methods can fill the gap in this field as they take into account the very different physical processes that occur during aerosol transport.

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Background: We investigated whether levosimendan prevents contrast medium nephrotoxicity with glycerol aggravation in rats.

Methods: Forty-eight Wistar albino rats were assigned to eight groups (n = 6 × 8). No medication was administered to group I (controls); glycerol (intramuscular injection of 25% glycerol, 10 mL/kg) group II; intravenous iohexol 10 mL/kg to group III; glycerol and iohexol to group IV; iohexol and intraperitoneal levosimendan 0.

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Purpose: This study aims to investigate the relationship between nurses' perceptions and their competences in spiritual care and influencing factors.

Design And Methods: This correlational study was conducted with 700 nurses. The Spirituality and Spiritual Care Rating Scale (SSCRS) was used to determine nurses' spirituality perceptions.

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Behçet's disease, an inflammatory condition, can involve various systems. The disease usually manifests with dermatologic and ocular signs but can also cause serious symptoms due to pulmonary or neurologic involvement. Although the onset may occur at any age, it typically emerges in the second to fourth decades of life.

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Anticoagulant therapy is a treatment that can cause bleeding complications in many anatomical structures. Intracranial, intramuscular and intraabdominal bleeding are internal bleeding that can be secondary to anticoagulated therapy. The prognosis of these hemorrhages can be very good, depending on the anatomical region involved, or they can be fatal.

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Melatonin improves fracture healing, but the long-term use of melatonin seems impracticable in the treatment of fracture due to side effects caused by hormonal stress on chronological rhythm. Ramelteon (RAMEL) and agomelatine (AGO) are non-selective peripheral melatonin receptor (MT) agonists. This study investigated the effects on bone fracture healing of these MT agonists, which do not affect the central nervous system.

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Article Synopsis
  • The sick lobe theory suggests specific breast lobes are more likely to develop cancer, but its impact on MRI findings has not been explored.
  • The study aimed to analyze MRI characteristics of mass and non-mass patterns in breast cancer cases and compare these with histopathological outcomes.
  • Results indicated that patients with mass patterns tended to have more malignant lesions, while non-mass patterns were associated with a higher rate of benign conditions, highlighting distinct malignancy risks based on the type of MRI pattern observed.
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Purpose: Silicosis is an incurable occupational disease that sometimes rapidly progresses with fatal outcomes. We aimed to evaluate the association between disease severity and the change in the pectoralis major muscle volume (PMV), subcutaneous fat volume (SFV), and the pulmonary artery/aorta (P/Ao) ratio in patients with silicosis using computed tomography (CT).

Methods: The study included 41 male silicosis patients and 41 control group subjects with available chest CT images.

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Acute respiratory distress syndrome is characterized by dyspnea at presentation, tachypnea on physical examination, findings of bilateral infiltration in chest radiography, refractory hypoxia, and high mortality. Although the main treatment approach is to address the underlying disease, there are also pharmacological and nonpharmacological options for supportive treatment. There is currently no pharmacological agent with proven efficacy in this syndrome, and many drugs are being studied for this purpose.

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Lung pathologies in the pediatric population can usually be detected using chest radiography. Multidetector computed tomography (MDCT) imaging is often used as a supplementary method in the evaluation of lung diseases. Recently, magnetic resonance imaging (MRI) techniques were found to be reliable in the evaluation of pulmonary diseases in the pediatric population.

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Objective: The aim of this study was to evaluate the compressive sonoelastography findings of primary esophageal carcinoma.

Materials And Methods: Esophageal specimens of the patients with a tumor staged earlier than T2, with no lymphadenopathy or distant metastasis, who underwent surgery, were evaluated by compressive sonoelastography under ex vivo conditions immediately following surgical excision. The compressive sonoelastography findings of primary esophageal carcinoma were recorded.

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BN has important roles in several physiological events, including bone growth and immune system. New infection-free cranioplasty and has an osteogenic activities material that are compatible with tissue are being developed. We aimed in our study to examine whether different combinations of Boron-nitride/Hydroxyapatite are embedded into the scaffold in the treatment of calvarial defects.

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Purpose: Obstructive sleep apnea syndrome (OSAS) is a condition resulting from repetitive partial or complete upper airway obstruction, and its etiology remains uncertain. Polysomnography is the gold standard diagnostic test for OSAS. However, there are long wait times for this evaluation, so questionnaires or ancillary diagnostic methods are used to select appropriate patients.

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