Publications by authors named "Adeline Brossaud"
Article Synopsis
- Adipokines, which are hormones secreted by white adipose tissue, influence reproductive functions in mammals and are also found in avian species, particularly in chicken egg albumen.
- The study focused on the presence of various adipokines (like adiponectin, visfatin, and apelin) and their receptors in the reproductive tract of hens and during embryo development, using methods like Western blot and RT-qPCR.
- Findings revealed that these adipokines are expressed variably depending on the hen's reproductive status and the egg's position in the oviduct, indicating their significant roles in regulating chicken embryo growth and suggesting their potential as biomarkers for improving development outcomes.
Embryo mortality rate, which can reach up to 40% in avian species, is a major issue for breeding. It is therefore important to identify new embryo development biomarkers for genetic selection to improve reproductive performances. We have recently shown that chemerin is expressed in the oviductal hen magnum, accumulates in egg white, is correlated with embryo survival and could thus be used as a molecular marker of embryo development.
View Article and Find Full Text PDFArticle Synopsis
- Research indicates that chemerin and its receptors (CMKLR1, GPR1, CCRL2) are crucial during chicken embryogenesis, with high chemerin levels found in albumen eggs compared to blood plasma.
- Chemerin, produced in the oviduct magnum, is influenced by hormones like progesterone and estrogen, and it appears in amniotic and chorioallantoic membranes, affecting embryo health and development.
- Inhibiting chemerin or CMKLR1 increases embryo mortality and decreases blood vessel formation, highlighting the importance of the chemerin system in embryo development and its potential as a fertility marker.
Some evidence shows that body mass index in humans and extreme weights in animal models, including avian species, are associated with low in vitro fertilization, bad oocyte quality, and embryo development failures. Adipokines are hormones mainly produced and released by white adipose tissue. They play a key role in the regulation of energy metabolism.
View Article and Find Full Text PDFArticle Synopsis
- Reactive oxygen species (ROS) contribute to oxidative stress which negatively impacts ovarian function, but grape seed extract (GSE) is suggested as a potential antioxidant due to its proanthocyanidin content.
- * In this study, various concentrations of GSE and proanthocyanidin B2 (GSPB2) were tested on ovarian cells (both primary and tumor-derived) to assess their effects on ROS levels, cell proliferation, viability, and steroid hormone production.
- * Results showed that lower doses (0.1 to 1 μg/mL) of GSE and GSPB2 reduced ROS levels and improved hormone secretion, while higher doses (50 to 100 μg/mL) led to adverse effects,