Publications by authors named "Adeline Boileau"

Thoracic aortic aneurysm (TAA) can lead to fatal complications such as aortic dissection. Since aneurysm dimension poorly predicts dissection risk, microRNAs (miRNAs) may be useful to diagnose or risk stratify TAA patients. We aim to identify miRNAs associated with TAA pathogenesis and that are possibly able to improve TAA diagnosis.

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Article Synopsis
  • - The study investigates the role of circulating microRNA miR-574-5p in predicting neurological outcomes in cardiac arrest patients, focusing on gender differences.
  • - Out of 590 enrolled patients, 49% experienced poor neurological outcomes, with higher levels of miR-574-5p found in these cases 48 hours post-arrest.
  • - While miR-574-5p was a strong predictor of poor outcomes in women, it did not show the same predictive power in men, highlighting the need for sex-specific approaches in postresuscitation prognosis.
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Thoracic aortic aneurysm (TAA) is an asymptomatic and progressive dilatation of the thoracic aorta. Ascending aortic dissection (AAD) is an acute intraparietal tear, occurring or not on a pre-existing dilatation. AAD is a condition associated with a poor prognosis and a high mortality rate.

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Background: Identification of patients at risk of poor outcome after acute myocardial infarction (MI) would allow tailoring healthcare to each individual. However, lack of prognostication tools renders this task challenging. Previous investigations suggested that blood transcriptome analysis may inform about prognosis after MI.

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. The value of microRNAs (miRNAs) as biomarkers has been addressed in various clinical contexts. Initial studies suggested that miRNAs, such as the brain-enriched miR-124-3p, might improve outcome prediction after out-of-hospital cardiac arrest.

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