Publications by authors named "Adelina Dillmann"
Hum Gene Ther Clin Dev
June 2013
Article Synopsis
- Chronic granulomatous disease (CGD) is an immune deficiency that affects the body's ability to fight infections, but gene therapy has shown potential as a treatment method in clinical trials.
- A new self-inactivating gammaretroviral vector (SINfes.gp91s) has been developed to deliver a gene that corrects the underlying issue in the X-linked form of CGD, showing promise in preclinical studies with mice.
- The new vector demonstrated effective protection against infections with low risks of harmful side effects, such as unwanted cell growth or cancer, indicating it may be a safer alternative for treating CGD.
