Impacts of gentamycin toxicity: nephroprotective role of guarana through different signaling pathways.

Gentamicin is a widely used aminoglycosidic antibiotic since its discovery. Like any other medication gentamicin causes unwanted side effects such as hepatotoxicity and nephrotoxicity. This study aims to examine the antioxidant effect of the guarana seed extract in protecting renal tissue.

Extract Potentially Inhibited Methicillin Resistant Induced Infection in Rabbits: Potential Immunomodulatory and Growth Promoting Properties.

Weaning is the most crucial period associated with increased stress and susceptibility to diseases in rabbits. Methicillin-resistant (MRSA), a historic emergent pathogen related to post weaning stressors, adversely affects rabbit's growth rate and productive cycle. Since MRSA is rapidly evolving antibiotics resistance, natural products are desperately required to tackle the public health threats posed by antimicrobial resistance.

Growth, carcass parameters, biochemical and oxidative stress indices, and meat traits of duck breeds under different stocking densities.

This investigation was aimed to inspect if there is an influence of various stocking density on growth, carcass parameters, blood indices, and meat traits of Muscovy and Mallard ducks. One hundred twenty-six 1-day-old of each Muscovy and Mallard ducks were randomly allocated into three experimental groups with different stocking density. Group one (SD) was 5 ducks/m, while group 2 (SD) was 7 ducks/m and group 3 (SD) was 9 ducks/m.

Reproductive Performance and Culling Rate of Purebred Holstein Cows and Their Crosses With Fleckvieh and Brown Swiss Cows Under Subtropical Conditions.

This study aimed to elucidate the reproductive performance of purebred Holstein (HO) cows with their crosses with Fleckvieh (FV) and Brown Swiss (BS) cows under subtropical conditions. A total of 677 cows [487 HO, 104 HO × FV (HFV); 50% FV and 50% HO and 86 HO × BS (HB); 50% BS and 50% HO] were enrolled in this study. Pure HO cows had significantly greater service per conception (S/C; 3.

Potential impact of stocking density on growth, carcass traits, indicators of biochemical and oxidative stress and meat quality of different broiler breeds.

The aim of the current study to investigate the potential impact of different stocking densities on growth performance, carcass traits, indicators of biochemical and oxidative stress and meat quality of Arbor Acres and Ross-308 broiler breeds to recommend the better stocking density with low production cost simultaneously with high quality. A total of 312 one-day old of each Arbor Acres broiler and Ross-308 were randomly classified into 3 experimental groups with different stocking density, each of 6 replicates. The first group (SD) was 14 birds/m (28 kg/m), while the second group (SD) was 18 birds/m (36 kg/m) and the third group (SD) was 20 birds/m (40 kg/m).

Ameliorative impacts of root extract against nephrotoxicity induced by gentamicin in mice.

Gentamicin is an effective antibiotic that has been used worldwide for many years. While considered an essential medicine by the WHO, gentamicin can also lead to severe kidney damage. This study explored the ameliorative effects of root extract on gentamicin-induced renal injury in mice.

Tobacco smoking causes secondary polycythemia and a mild leukocytosis among heavy smokers in Taif City in Saudi Arabia.

Tobacco smoking is a common risk factor of cardiovascular diseases, cancers and heart health problems. In Taif, the number of secondary polycythemia patients is increasing dramatically and most of those patients are heavy smokers. Therefore, this study is an attempt to understand the pathophysiological mechanism behind that problem.

Anti-inflammatory Effect of Juniperus Procera Extract in Rats Exposed to Streptozotocin Toxicity.

Background: Chronic inflammation is a critical health issue and implicated in several chronic health problems such as tumors, auto-immune disorder, hypertension or diabetes. However, Juniperus procera is one of the famous ancient plants that has been traditionally used to treat several diseases such as hyperglycemia, hepatitis, jaundice, bronchitis, and pneumonia.

Objective: Current study is an attempt to investigate the anti-inflammatory effect of Juniperus procera extract on rats exposed to cytotoxicity caused experimentally by streptozotocin injections.

Preventive effect of Juniperus procera extract on liver injury induced by lithocholic acid.

Bile acids are strong cytotoxic endogenous compounds implicated in several diseases in various organs, such as the liver, gallbladder and small and large intestines. Lithocholic acid is one such acid, produced by flora, and causes liver injury, cholestasis, and colon cancer. The present study aimed to examine the preventive effects of Juniperus procera extract on lithocholic acid‑induced liver injury in experimental mice.

Preventive effect of artemisinin extract against cholestasis induced via lithocholic acid exposure.

Obstructive cholestasis characterized by biliary pressure increase leading to leakage of bile back that causes liver injury. The present study aims to evaluate the effects of artemisinin in obstructive cholestasis in mice. The present study was carried out on 40 adult healthy mice that were divided into 4 groups, 10 mice each; the negative control group didn't receive any medication.

Association of Learning and Memory Calcineurin Binding Protein with Autism Spectrum Disorders.

Objective: To determine the association of learning and memory calcineurin binding (CABIN1) protein with autism spectrum disorders.

Study Design: Cross-sectional comparative study.

Place And Duration Of Study: The Autism Research and Treatment Center, King Khalid University Hospital, Riyadh, Saudi Arabia, from October 2013 to May 2014.