Publications by authors named "Adel Muhanna"

Background: Lymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate cutoff ratios require validation. We aimed to study the prognostic significance of LNR and its optimal cutoff ratio.

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  • Alcoholic liver disease (ALD) is a major cause for liver transplants in the U.S., and the COVID-19 pandemic has potentially worsened the situation due to increased alcohol consumption.
  • A study compared ALD admissions before and during the pandemic across four hospitals, revealing a significant rise in admissions during the pandemic, especially among younger women.
  • The findings highlight concerning trends, particularly the rapid progression of ALD in women, underscoring the need for preventive health measures.
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  • A systematic review was conducted to evaluate the association between celiac disease (CD) and microscopic colitis (MC) by analyzing published studies, following PRISMA guidelines.
  • The study included 26 studies with 22,802 MC patients, finding a strong statistical association between CD and MC (odds ratio 8.276).
  • The analysis revealed a significant prevalence of CD in both types of MC, with gastroenterologists advised to consider this connection when treating patients showing poor response to standard therapies.
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Testicular germ cell tumors account for 95% of testicular cancers in men with approximately 71,000 patients being diagnosed with testicular cancer every year. The overall survival of testicular germ cell tumors is approximately 95%. However, the prognosis becomes less favorable when distant metastasis is present.

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Sarcoidosis is an autoimmune disease, which most commonly affects the lungs and lymph nodes and is characterized with non-caseating granulomas. Hepatic involvement in sarcoidosis occurs in less than 1% of patients. Most patients with hepatic sarcoidosis remain asymptomatic with only laboratory abnormalities.

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 is the most common endemic mycosis in the United States and usually occurs in certain geographic areas, such as the Mississippi or Ohio River valleys. Histoplasmosis usually causes a mild disease in the immunocompetent but can progress to disseminated disease in patients with impaired immunity. Granulomatous hepatitis as a manifestation of disseminated histoplasmosis in immunocompetent patients is extremely rare.

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