Early detection of heart issues in thalassemia patients is crucial, and four-dimensional echocardiography may help identify early cardiovascular problems.
A study involving 200 children (100 with beta thalassemia major and 100 healthy controls) examined various echocardiographic factors, finding significant differences in ejection fraction, left ventricle mass, and other parameters.
The study revealed that children with thalassemia had notably lower left ventricular strain values compared to controls, indicating potential heart dysfunction despite no clinical symptoms.